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NCT00112528 · ClinicalTrials.gov registry record · Phase 2

Bevacizumab, Gemcitabine, and Oxaliplatin in Treating Patients With Metastatic Pancreatic Cancer

A Phase 2 study, sponsored by Alliance for Clinical Trials in Oncology.

Completed
Registry status
Phase 2
Development phase
53
Enrollment target

NCT00112528: Completed Phase 2 study, sponsored by Alliance for Clinical Trials in Oncology.

NCT00112528 is a Phase 2 study that has completed, run by Alliance for Clinical Trials in Oncology. The registered enrollment target is 53 participants, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (60% lower). According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT00112528, a Phase 2 study, has completed, sponsored by Alliance for Clinical Trials in Oncology.

COMPLETED
Registry status
Phase 2
Development phase
53 participants
Enrollment target

Study Summary

RATIONALE: Monoclonal antibodies, such as bevacizumab, can block tumor growth in different ways. Some block the ability of tumor cells to grow and spread. Others find tumor cells and help kill them or carry tumor-killing substances to them. Bevacizumab may also stop the growth of pancreatic cancer by blocking blood flow to the tumor. Drugs used in chemotherapy, such as gemcitabine and oxaliplatin, work in different ways to stop the growth of tumor cells, either by killing the cells or by stopping them from dividing. Giving bevacizumab together with gemcitabine and oxaliplatin may kill more tumor cells. PURPOSE: This phase II trial is studying how well giving bevacizumab together with gemcitabine and oxaliplatin works in treating patients with metastatic pancreatic cancer.

Interventions

  • DRUG oxaliplatin
  • BIOLOGICAL bevacizumab
  • DRUG gemcitabine hydrochloride

Trial Details

FieldValue
Enrollment Target 53 participants
Start Date 2005-06
Est. Completion 2010-11
Phase Phase 2

What the finished NCT00112528 record still lists

NCT00112528 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 53 participants, a relatively small participant target, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (60% lower).

The record links to 0 conditions, and to 3 interventions - of which oxaliplatin is the first listed.

NCT00112528 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT00112528 about?

NCT00112528 is a clinical study titled "Bevacizumab, Gemcitabine, and Oxaliplatin in Treating Patients With Metastatic Pancreatic Cancer". RATIONALE: Monoclonal antibodies, such as bevacizumab, can block tumor growth in different ways. Some block the ability of tumor cells to grow and spread. Others find tumor cells and help kill them or carry tumor-killing substances to them. Bevacizumab may also stop the growth of pancreatic cancer b...

What is the current status of trial NCT00112528?

This trial is currently completed. It is a Phase 2 study. The enrollment target is 53 participants. The study started on 2005-06. Estimated completion is 2010-11.

What interventions are being tested in trial NCT00112528?

The interventions under investigation include: oxaliplatin (DRUG), bevacizumab (BIOLOGICAL), gemcitabine hydrochloride (DRUG).

Who is sponsoring clinical trial NCT00112528?

This trial is sponsored by Alliance for Clinical Trials in Oncology, which has 446 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT00112528's enrollment target sits among peer trials

53 1171st of 2000 higher than 820 of 2,000 other Phase 2 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Phase 2 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT00112528, the US trial registry maintained by the National Library of Medicine. NCT00112528 (small enrollment · none site footprint · completed) retrieved and formatted by PlainTrial, see methodology.