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NCT00105976 · ClinicalTrials.gov registry record · Phase 2
Efficacy Study of MM-093 in Rheumatoid Arthritis Patients on Methotrexate (MTX)
A Phase 2 study, sponsored by Merrimack Pharmaceuticals.
- Completed
- Registry status
- Phase 2
- Development phase
- 260
- Enrollment target
NCT00105976 is a Phase 2 study that has completed, run by Merrimack Pharmaceuticals. The registered enrollment target is 260 participants.
The verdict
NCT00105976, a Phase 2 study, has completed, sponsored by Merrimack Pharmaceuticals.
- COMPLETED
- Registry status
- Phase 2
- Development phase
- 260 participants
- Enrollment target
Study Summary
The purpose of this clinical study is to see if an experimental drug, called MM-093, is safe and effective in the treatment of rheumatoid arthritis. MM-093 is a genetically engineered version of a naturally occurring protein called alpha fetoprotein (AFP). Adults normally have very small amounts of AFP in their bloodstream. However, during pregnancy, AFP levels in both the mother and the fetus are much higher than normal. It has been observed that women with RA (Rheumatoid Arthritis) have fewer symptoms during pregnancy, particularly during the third trimester. At this time, the levels of AFP in the blood of the mother and fetus are the highest. This observation led researchers to begin examining AFP as a possible treatment for RA.
Interventions
- DRUG MM-093
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 260 participants |
| Start Date | 2005-02 |
| Phase | Phase 2 |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT00105976
The ClinicalTrials.gov registry entry for NCT00105976 describes a study currently listed as completed, categorized as Phase 2. The registered enrollment target is 260 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Merrimack Pharmaceuticals, which has 22 total studies on file at ClinicalTrials.gov.
The record links to 0 conditions, and to 1 intervention - of which MM-093 is the first listed.
NCT00105976 reports 0 study locations.
Frequently Asked Questions
What is clinical trial NCT00105976 about?
NCT00105976 is a clinical study titled "Efficacy Study of MM-093 in Rheumatoid Arthritis Patients on Methotrexate (MTX)". The purpose of this clinical study is to see if an experimental drug, called MM-093, is safe and effective in the treatment of rheumatoid arthritis. MM-093 is a genetically engineered version of a naturally occurring protein called alpha fetoprotein (AFP). Adults normally have very small amounts of ...
What is the current status of trial NCT00105976?
This trial is currently completed. It is a Phase 2 study. The enrollment target is 260 participants. The study started on 2005-02.
What interventions are being tested in trial NCT00105976?
The interventions under investigation include: MM-093 (DRUG).
Who is sponsoring clinical trial NCT00105976?
This trial is sponsored by Merrimack Pharmaceuticals, which has 22 total clinical trials registered on ClinicalTrials.gov.
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