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NCT00101179 · ClinicalTrials.gov registry record · Phase 1

MS-275 and Azacitidine in Treating Patients With Myelodysplastic Syndromes, Chronic Myelomonocytic Leukemia, or Acute Myeloid Leukemia

A Phase 1 study, sponsored by National Cancer Institute (NCI).

Completed
Registry status
Phase 1
Development phase
63
Enrollment target

NCT00101179: Completed Phase 1 study, sponsored by National Cancer Institute (NCI).

NCT00101179 is a Phase 1 study that has completed, run by National Cancer Institute (NCI). The registered enrollment target is 63 participants. According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT00101179, a Phase 1 study, has completed, sponsored by National Cancer Institute (NCI).

COMPLETED
Registry status
Phase 1
Development phase
63 participants
Enrollment target

Study Summary

MS-275 may stop the growth of cancer cells by blocking some of the enzymes needed for cell growth. Drugs used in chemotherapy, such as azacitidine, work in different ways to stop the growth of cancer cells, either by killing the cells or by stopping them from dividing. Giving MS-275 together with azacitidine may kill more cancer cells. This phase I trial is studying the side effects and best dose of MS-275 when given together with azacitidine in treating patients with myelodysplastic syndromes, chronic myelomonocytic leukemia, or acute myeloid leukemia.

Interventions

  • DRUG Azacitidine
  • DRUG Entinostat

Trial Details

FieldValue
Enrollment Target 63 participants
Start Date 2004-11-03
Est. Completion 2014-02-03
Phase Phase 1

Sponsor

National Cancer Institute (NCI)

3,257 total trials

What the Registry Record Tells You About NCT00101179

The ClinicalTrials.gov registry entry for NCT00101179 describes a study currently listed as completed, categorized as Phase 1. The registered enrollment target is 63 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is National Cancer Institute (NCI), which has 3,257 total studies on file at ClinicalTrials.gov.

The record links to 0 conditions, and to 2 interventions - of which Azacitidine is the first listed.

NCT00101179 reports 0 study locations.

Frequently Asked Questions

What is clinical trial NCT00101179 about?

NCT00101179 is a clinical study titled "MS-275 and Azacitidine in Treating Patients With Myelodysplastic Syndromes, Chronic Myelomonocytic Leukemia, or Acute Myeloid Leukemia". MS-275 may stop the growth of cancer cells by blocking some of the enzymes needed for cell growth. Drugs used in chemotherapy, such as azacitidine, work in different ways to stop the growth of cancer cells, either by killing the cells or by stopping them from dividing. Giving MS-275 together with az...

What is the current status of trial NCT00101179?

This trial is currently completed. It is a Phase 1 study. The enrollment target is 63 participants. The study started on 2004-11-03. Estimated completion is 2014-02-03.

What interventions are being tested in trial NCT00101179?

The interventions under investigation include: Azacitidine (DRUG), Entinostat (DRUG).

Who is sponsoring clinical trial NCT00101179?

This trial is sponsored by National Cancer Institute (NCI), which has 3,257 total clinical trials registered on ClinicalTrials.gov.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.