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NCT00091026 · ClinicalTrials.gov registry record · Phase 2

Bevacizumab and Gemcitabine Combined With Either Cetuximab or Erlotinib in Treating Patients With Advanced Pancreatic Cancer

A Phase 2 study, sponsored by National Cancer Institute (NCI).

Completed
Registry status
Phase 2
Development phase
143
Enrollment target

NCT00091026: Completed Phase 2 study, sponsored by National Cancer Institute (NCI).

NCT00091026 is a Phase 2 study that has completed, run by National Cancer Institute (NCI). The registered enrollment target is 143 participants, roughly in line with the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target. According to ClinicalTrials.gov, the official US trial registry.

View on ClinicalTrials.gov ↗

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The verdict

NCT00091026, a Phase 2 study, has completed, sponsored by National Cancer Institute (NCI).

COMPLETED
Registry status
Phase 2
Development phase
143 participants
Enrollment target

Study Summary

This randomized phase II trial is studying bevacizumab, gemcitabine, and cetuximab to see how well they work compared to bevacizumab, gemcitabine, and erlotinib in treating patients with advanced pancreatic cancer. Monoclonal antibodies, such as cetuximab and bevacizumab, can locate tumor cells and either kill them or deliver tumor-killing substances to them without harming normal cells. Drugs used in chemotherapy, such as gemcitabine, work in different ways to stop tumor cells from dividing so they stop growing or die. Erlotinib may stop the growth of tumor cells by blocking the enzymes necessary for their growth. Combining bevacizumab and gemcitabine with either cetuximab or erlotinib may kill more tumor cells.

Interventions

  • BIOLOGICAL cetuximab
  • BIOLOGICAL bevacizumab
  • DRUG gemcitabine hydrochloride
  • DRUG erlotinib hydrochloride

Trial Details

FieldValue
Enrollment Target 143 participants
Start Date 2004-07
Est. Completion 2011-01
Phase Phase 2
National Cancer Institute (NCI)

3,257 total trials

What the finished NCT00091026 record still lists

NCT00091026 is an interventional study that assigns participants to a tested intervention. The registered 143 participants enrollment target is mid-sized for trials with a published cap, roughly in line with the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target.

The record links to 0 conditions, and to 4 interventions - of which cetuximab is the first listed.

NCT00091026 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT00091026 about?

NCT00091026 is a clinical study titled "Bevacizumab and Gemcitabine Combined With Either Cetuximab or Erlotinib in Treating Patients With Advanced Pancreatic Cancer". This randomized phase II trial is studying bevacizumab, gemcitabine, and cetuximab to see how well they work compared to bevacizumab, gemcitabine, and erlotinib in treating patients with advanced pancreatic cancer. Monoclonal antibodies, such as cetuximab and bevacizumab, can locate tumor cells and ...

What is the current status of trial NCT00091026?

This trial is currently completed. It is a Phase 2 study. The enrollment target is 143 participants. The study started on 2004-07. Estimated completion is 2011-01.

What interventions are being tested in trial NCT00091026?

The interventions under investigation include: cetuximab (BIOLOGICAL), bevacizumab (BIOLOGICAL), gemcitabine hydrochloride (DRUG), erlotinib hydrochloride (DRUG).

Who is sponsoring clinical trial NCT00091026?

This trial is sponsored by National Cancer Institute (NCI), which has 3,257 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT00091026's enrollment target sits among peer trials

143 507th of 2000 higher than 1,494 of 2,000 other Phase 2 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Phase 2 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT00091026, the US trial registry maintained by the National Library of Medicine. NCT00091026 (mid enrollment · none site footprint · completed) retrieved and formatted by PlainTrial, see methodology.