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NCT00089245 · ClinicalTrials.gov registry record · Phase 1
Radiolabeled MAB Therapy in Patients With Refractory, Recurrent, or Advanced CNS or Leptomeningeal Cancer
A Phase 1 study, sponsored by Y-mAbs Therapeutics.
- Terminated
- Registry status
- Phase 1
- Development phase
- 177
- Enrollment target
NCT00089245: Clinical Trial Phase 1 study, sponsored by Y-mAbs Therapeutics.
NCT00089245 is a Phase 1 study that was terminated before completion, run by Y-mAbs Therapeutics. The registered enrollment target is 177 participants, above the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (195% higher). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT00089245, a Phase 1 study, was terminated before completion, sponsored by Y-mAbs Therapeutics.
- TERMINATED
- Registry status
- Phase 1
- Development phase
- 177 participants
- Enrollment target
Study Summary
The purpose of this study is to test the feasibility and toxicity of administering intrathecal immunotherapy for patients with central nervous system/leptomeningeal (CNS/LM) malignancies.
Primary Outcome
Assessment of patient with treatment related toxicities
Interventions
- DRUG Iodine I 131 MOAB 8H9
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 177 participants |
| Start Date | 2004-02-05 |
| Est. Completion | 2022-02-02 |
| Phase | Phase 1 |
Why NCT00089245 stopped before completion
NCT00089245 is an interventional study that assigns participants to a tested intervention. The registered 177 participants enrollment target is mid-sized for trials with a published cap, above the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (195% higher).
The record links to 0 conditions, and to 1 intervention - of which Iodine I 131 MOAB 8H9 is the first listed.
NCT00089245 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT00089245 about?
NCT00089245 is a clinical study titled "Radiolabeled MAB Therapy in Patients With Refractory, Recurrent, or Advanced CNS or Leptomeningeal Cancer". The purpose of this study is to test the feasibility and toxicity of administering intrathecal immunotherapy for patients with central nervous system/leptomeningeal (CNS/LM) malignancies.
What is the current status of trial NCT00089245?
This trial is currently terminated. It is a Phase 1 study. The enrollment target is 177 participants. The study started on 2004-02-05. Estimated completion is 2022-02-02.
What interventions are being tested in trial NCT00089245?
The interventions under investigation include: Iodine I 131 MOAB 8H9 (DRUG).
Who is sponsoring clinical trial NCT00089245?
This trial is sponsored by Y-mAbs Therapeutics, which has 11 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT00089245's enrollment target sits among peer trials
177 313th of 2000 higher than 1,685 of 2,000 other Phase 1 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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