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NCT00087451 · ClinicalTrials.gov registry record · Phase 1
Safety Study of AP23573 in Patients With Progressive or Recurrent Glioma (8669-023)(COMPLETED)
A Phase 1 study, sponsored by Merck Sharp & Dohme.
- Completed
- Registry status
- Phase 1
- Development phase
- 11
- Enrollment target
NCT00087451: Completed Phase 1 study, sponsored by Merck Sharp & Dohme.
NCT00087451 is a Phase 1 study that has completed, run by Merck Sharp & Dohme. The registered enrollment target is 11 participants, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (82% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT00087451, a Phase 1 study, has completed, sponsored by Merck Sharp & Dohme.
- COMPLETED
- Registry status
- Phase 1
- Development phase
- 11 participants
- Enrollment target
Study Summary
A Phase I, open-label, non-randomized, sequential dose escalation cohort trial of the safety, tolerability, and maximum tolerated dose (MTD) of AP23573 when administered intravenously as a 30-minute infusion, once daily for five days, repeated every two weeks, to patients with progressive or recurrent malignant glioma.
Interventions
- DRUG AP23573
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 11 participants |
| Start Date | 2004-07 |
| Est. Completion | 2005-11 |
| Phase | Phase 1 |
What the finished NCT00087451 record still lists
NCT00087451 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 11 participants, a relatively small participant target, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (82% lower).
The record links to 0 conditions, and to 1 intervention - of which AP23573 is the first listed.
NCT00087451 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT00087451 about?
NCT00087451 is a clinical study titled "Safety Study of AP23573 in Patients With Progressive or Recurrent Glioma (8669-023)(COMPLETED)". A Phase I, open-label, non-randomized, sequential dose escalation cohort trial of the safety, tolerability, and maximum tolerated dose (MTD) of AP23573 when administered intravenously as a 30-minute infusion, once daily for five days, repeated every two weeks, to patients with progressive or recurre...
What is the current status of trial NCT00087451?
This trial is currently completed. It is a Phase 1 study. The enrollment target is 11 participants. The study started on 2004-07. Estimated completion is 2005-11.
What interventions are being tested in trial NCT00087451?
The interventions under investigation include: AP23573 (DRUG).
Who is sponsoring clinical trial NCT00087451?
This trial is sponsored by Merck Sharp & Dohme, which has 558 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT00087451's enrollment target sits among peer trials
11 1911th of 2000 higher than 88 of 2,000 other Phase 1 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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