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NCT00087178 · ClinicalTrials.gov registry record · Phase 3
Comparison of Two Combination Chemotherapy Regimens in Treating Women With Breast Cancer
A Phase 3 study, sponsored by NSABP Foundation.
- Completed
- Registry status
- Phase 3
- Development phase
- 2,722
- Enrollment target
NCT00087178: Completed Phase 3 study, sponsored by NSABP Foundation.
NCT00087178 is a Phase 3 study that has completed, run by NSABP Foundation. The registered enrollment target is 2,722 participants, above the 772-participant average among 15,282 other Phase 3 trials with a reported enrollment target (253% higher). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT00087178, a Phase 3 study, has completed, sponsored by NSABP Foundation.
- COMPLETED
- Registry status
- Phase 3
- Development phase
- 2,722 participants
- Enrollment target
Study Summary
RATIONALE: Drugs used in chemotherapy, such as fluorouracil, epirubicin, cyclophosphamide, and doxorubicin, work in different ways to stop tumor cells from dividing so they stop growing or die. It is not yet known which combination chemotherapy regimen is more effective in treating breast cancer. PURPOSE: This randomized phase III trial is studying two combination chemotherapy regimens to compare how well they work in treating women who have undergone surgery for breast cancer that has not spread to the lymph nodes.
Primary Outcome
Percentage of patients free from DFS event. DFS events include local, regional, or distant recurrence, second primary cancer or death from any cause prior to recurrence or second primary cancer
Interventions
- DRUG cyclophosphamide
- DRUG fluorouracil
- DRUG epirubicin
- DRUG adriamycin
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 2,722 participants |
| Start Date | 2004-05 |
| Est. Completion | 2016-05 |
| Phase | Phase 3 |
What the finished NCT00087178 record still lists
NCT00087178 is an interventional study that assigns participants to a tested intervention. Its 2,722 participants enrollment target places it among the larger protocols in the corpus, above the 772-participant average among 15,282 other Phase 3 trials with a reported enrollment target (253% higher).
The record links to 0 conditions, and to 4 interventions - of which cyclophosphamide is the first listed.
NCT00087178 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT00087178 about?
NCT00087178 is a clinical study titled "Comparison of Two Combination Chemotherapy Regimens in Treating Women With Breast Cancer". RATIONALE: Drugs used in chemotherapy, such as fluorouracil, epirubicin, cyclophosphamide, and doxorubicin, work in different ways to stop tumor cells from dividing so they stop growing or die. It is not yet known which combination chemotherapy regimen is more effective in treating breast cancer. P...
What is the current status of trial NCT00087178?
This trial is currently completed. It is a Phase 3 study. The enrollment target is 2,722 participants. The study started on 2004-05. Estimated completion is 2016-05.
What interventions are being tested in trial NCT00087178?
The interventions under investigation include: cyclophosphamide (DRUG), fluorouracil (DRUG), epirubicin (DRUG), adriamycin (DRUG).
Who is sponsoring clinical trial NCT00087178?
This trial is sponsored by NSABP Foundation, which has 44 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT00087178's enrollment target sits among peer trials
2,722 83rd of 2000 higher than 1,918 of 2,000 other Phase 3 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 3 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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