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NCT00077233 · ClinicalTrials.gov registry record · Phase 3
FOLFIRI or FOLFOX With or Without Cetuximab in Patients With Metastatic Adenocarcinoma of the Colon or Rectum
A Phase 3 study, sponsored by Alliance for Clinical Trials in Oncology.
- Terminated
- Registry status
- Phase 3
- Development phase
- 238
- Enrollment target
NCT00077233: Clinical Trial Phase 3 study, sponsored by Alliance for Clinical Trials in Oncology.
NCT00077233 is a Phase 3 study that was terminated before completion, run by Alliance for Clinical Trials in Oncology. The registered enrollment target is 238 participants, below the 772-participant average among 15,282 other Phase 3 trials with a reported enrollment target (69% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT00077233, a Phase 3 study, was terminated before completion, sponsored by Alliance for Clinical Trials in Oncology.
- TERMINATED
- Registry status
- Phase 3
- Development phase
- 238 participants
- Enrollment target
Study Summary
This is a randomized phase II study trial that has served as a screening trial to test the increased efficacy of chemotherapy + cetuximab versus chemotherapy alone among patients with untreated, advanced or metastatic colon cancer regardless of tumor status with respect to EGFR.
Interventions
- DRUG cetuximab
- DRUG 5-FU
- DRUG oxaliplatin
- DRUG leucovorin
- DRUG irinotecan
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 238 participants |
| Start Date | 2003-12 |
| Est. Completion | 2010-06 |
| Phase | Phase 3 |
Why NCT00077233 stopped before completion
NCT00077233 is an interventional study that assigns participants to a tested intervention. The registered 238 participants enrollment target is mid-sized for trials with a published cap, below the 772-participant average among 15,282 other Phase 3 trials with a reported enrollment target (69% lower).
The record links to 0 conditions, and to 5 interventions - of which cetuximab is the first listed.
NCT00077233 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT00077233 about?
NCT00077233 is a clinical study titled "FOLFIRI or FOLFOX With or Without Cetuximab in Patients With Metastatic Adenocarcinoma of the Colon or Rectum". This is a randomized phase II study trial that has served as a screening trial to test the increased efficacy of chemotherapy + cetuximab versus chemotherapy alone among patients with untreated, advanced or metastatic colon cancer regardless of tumor status with respect to EGFR.
What is the current status of trial NCT00077233?
This trial is currently terminated. It is a Phase 3 study. The enrollment target is 238 participants. The study started on 2003-12. Estimated completion is 2010-06.
What interventions are being tested in trial NCT00077233?
The interventions under investigation include: cetuximab (DRUG), 5-FU (DRUG), oxaliplatin (DRUG), leucovorin (DRUG), irinotecan (DRUG).
Who is sponsoring clinical trial NCT00077233?
This trial is sponsored by Alliance for Clinical Trials in Oncology, which has 446 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT00077233's enrollment target sits among peer trials
238 1291st of 2000 higher than 708 of 2,000 other Phase 3 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 3 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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