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NCT00072761 · ClinicalTrials.gov registry record · Phase 3
Silent Cerebral Infarct Transfusion Multi-Center Clinical Trial
A Phase 3 study, sponsored by Washington University School of Medicine.
- Completed
- Registry status
- Phase 3
- Development phase
- 196
- Enrollment target
NCT00072761: Completed Phase 3 study, sponsored by Washington University School of Medicine.
NCT00072761 is a Phase 3 study that has completed, run by Washington University School of Medicine. The registered enrollment target is 196 participants, below the 772-participant average among 15,282 other Phase 3 trials with a reported enrollment target (75% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT00072761, a Phase 3 study, has completed, sponsored by Washington University School of Medicine.
- COMPLETED
- Registry status
- Phase 3
- Development phase
- 196 participants
- Enrollment target
Study Summary
The goal of this study is to determine the effectiveness of blood transfusion therapy for prevention of silent cerebral infarct (stroke) in children with sickle cell anemia.
Primary Outcome
The primary end point was the recurrence of infarct or hemorrhage as determined by neuroimaging, clinical evidence of permanent neurologic injury, or both. A new infarct had to meet the criteria for a silent cerebral infarction; an enlarged silent cerebral infarct was defined as a previously identified silent cerebral infarct that increased by at least 3 mm along any linear dimension in any plane on MRI.
Interventions
- PROCEDURE transfusion therapy
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 196 participants |
| Start Date | 2004-12 |
| Est. Completion | 2013-12 |
| Phase | Phase 3 |
What the finished NCT00072761 record still lists
NCT00072761 is an interventional study that assigns participants to a tested intervention. The registered 196 participants enrollment target is mid-sized for trials with a published cap, below the 772-participant average among 15,282 other Phase 3 trials with a reported enrollment target (75% lower).
The record links to 0 conditions, and to 1 intervention - of which transfusion therapy is the first listed.
NCT00072761 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT00072761 about?
NCT00072761 is a clinical study titled "Silent Cerebral Infarct Transfusion Multi-Center Clinical Trial". The goal of this study is to determine the effectiveness of blood transfusion therapy for prevention of silent cerebral infarct (stroke) in children with sickle cell anemia.
What is the current status of trial NCT00072761?
This trial is currently completed. It is a Phase 3 study. The enrollment target is 196 participants. The study started on 2004-12. Estimated completion is 2013-12.
What interventions are being tested in trial NCT00072761?
The interventions under investigation include: transfusion therapy (PROCEDURE).
Who is sponsoring clinical trial NCT00072761?
This trial is sponsored by Washington University School of Medicine, which has 1,502 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT00072761's enrollment target sits among peer trials
196 1390th of 2000 higher than 608 of 2,000 other Phase 3 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 3 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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