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NCT00066066 · ClinicalTrials.gov registry record · Phase 2
Effect of Three Periodontal Therapies in Current Smokers and Non-Smokers
A Phase 2 study, sponsored by The Forsyth Institute.
- Completed
- Registry status
- Phase 2
- Development phase
- 146
- Enrollment target
NCT00066066: Completed Phase 2 study, sponsored by The Forsyth Institute.
NCT00066066 is a Phase 2 study that has completed, run by The Forsyth Institute. The registered enrollment target is 146 participants, above the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (10% higher). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT00066066, a Phase 2 study, has completed, sponsored by The Forsyth Institute.
- COMPLETED
- Registry status
- Phase 2
- Development phase
- 146 participants
- Enrollment target
Study Summary
The purpose of this study is to determine in current and non-smokers the clinical and microbiological effects of 3 therapies: scaling and root planing (SRP) alone; SRP in combination with the orally administered antibiotic metronidazole; and SRP with the orally administered antibiotics metronidazole and amoxicillin along with the locally delivered antibiotic doxycycline at periodontal pockets \>= 4 mm.
Primary Outcome
Periodontal diseases are clinically diagnosed by assessments of gingival inflammation and measurements of tissue destruction. The damage to the apparatus of support of the teeth is quantified using measurements of probing pocket depth (PD) and clinical attachment level (CAL). These measurements are obtained using a periodontal probe which is introduced into the gingival sulcus to determine the distance in millimeters from the gingival margin to the depth of the sulcus or pocket (PD). Since the g
Interventions
- DRUG Amoxicillin
- DRUG Metronidazole
- DRUG Doxycycline
- PROCEDURE Scaling and root planing
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 146 participants |
| Start Date | 2003-07 |
| Est. Completion | 2009-07 |
| Phase | Phase 2 |
What the finished NCT00066066 record still lists
NCT00066066 is an interventional study that assigns participants to a tested intervention. The registered 146 participants enrollment target is mid-sized for trials with a published cap, above the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (10% higher).
The record links to 0 conditions, and to 4 interventions - of which Amoxicillin is the first listed.
NCT00066066 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT00066066 about?
NCT00066066 is a clinical study titled "Effect of Three Periodontal Therapies in Current Smokers and Non-Smokers". The purpose of this study is to determine in current and non-smokers the clinical and microbiological effects of 3 therapies: scaling and root planing (SRP) alone; SRP in combination with the orally administered antibiotic metronidazole; and SRP with the orally administered antibiotics metronidazole...
What is the current status of trial NCT00066066?
This trial is currently completed. It is a Phase 2 study. The enrollment target is 146 participants. The study started on 2003-07. Estimated completion is 2009-07.
What interventions are being tested in trial NCT00066066?
The interventions under investigation include: Amoxicillin (DRUG), Metronidazole (DRUG), Doxycycline (DRUG), Scaling and root planing (PROCEDURE).
Who is sponsoring clinical trial NCT00066066?
This trial is sponsored by The Forsyth Institute, which has 6 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT00066066's enrollment target sits among peer trials
146 496th of 2000 higher than 1,503 of 2,000 other Phase 2 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 2 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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