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NCT00066027 · ClinicalTrials.gov registry record · Phase 3
Effects of Low-Dose Doxycycline on Oral Bone Loss
A Phase 3 study, sponsored by University of Nebraska.
- Completed
- Registry status
- Phase 3
- Development phase
- 128
- Enrollment target
NCT00066027: Completed Phase 3 study, sponsored by University of Nebraska.
NCT00066027 is a Phase 3 study that has completed, run by University of Nebraska. The registered enrollment target is 128 participants, below the 772-participant average among 15,282 other Phase 3 trials with a reported enrollment target (83% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT00066027, a Phase 3 study, has completed, sponsored by University of Nebraska.
- COMPLETED
- Registry status
- Phase 3
- Development phase
- 128 participants
- Enrollment target
Study Summary
The primary purpose of this clinical trial is to determine whether low-dose doxycycline can reduce alveolar bone density loss in postmenopausal osteopenic women with periodontitis and not on hormone replacement therapy (i.e., estrogen deficient).
Primary Outcome
Alveolar bone density changes assessed by radiographic absorptiometry and computer-assisted densitometric image analysis.
Interventions
- DRUG Placebo
- DRUG 20 mg doxycycline hyclate
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 128 participants |
| Start Date | 2002-06-01 |
| Est. Completion | 2005-10-01 |
| Phase | Phase 3 |
What the finished NCT00066027 record still lists
NCT00066027 is an interventional study that assigns participants to a tested intervention. The registered 128 participants enrollment target is mid-sized for trials with a published cap, below the 772-participant average among 15,282 other Phase 3 trials with a reported enrollment target (83% lower).
The record links to 0 conditions, and to 2 interventions - of which Placebo is the first listed.
NCT00066027 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT00066027 about?
NCT00066027 is a clinical study titled "Effects of Low-Dose Doxycycline on Oral Bone Loss". The primary purpose of this clinical trial is to determine whether low-dose doxycycline can reduce alveolar bone density loss in postmenopausal osteopenic women with periodontitis and not on hormone replacement therapy (i.e., estrogen deficient).
What is the current status of trial NCT00066027?
This trial is currently completed. It is a Phase 3 study. The enrollment target is 128 participants. The study started on 2002-06-01. Estimated completion is 2005-10-01.
What interventions are being tested in trial NCT00066027?
The interventions under investigation include: Placebo (DRUG), 20 mg doxycycline hyclate (DRUG).
Who is sponsoring clinical trial NCT00066027?
This trial is sponsored by University of Nebraska, which has 407 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT00066027's enrollment target sits among peer trials
128 1601st of 2000 higher than 399 of 2,000 other Phase 3 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 3 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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