Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.

NCT00057356 · ClinicalTrials.gov registry record · Phase 2

Safety and Efficacy Study of YM087 (Conivaptan) in Patients With Acute Decompensated Heart Failure

A Phase 2 study, sponsored by Cumberland Pharmaceuticals.

Completed
Registry status
Phase 2
Development phase
170
Enrollment target

NCT00057356: Completed Phase 2 study, sponsored by Cumberland Pharmaceuticals.

NCT00057356 is a Phase 2 study that has completed, run by Cumberland Pharmaceuticals. The registered enrollment target is 170 participants, above the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (28% higher). According to ClinicalTrials.gov, the official US trial registry.

View on ClinicalTrials.gov ↗

View your shortlist →

The verdict

NCT00057356, a Phase 2 study, has completed, sponsored by Cumberland Pharmaceuticals.

COMPLETED
Registry status
Phase 2
Development phase
170 participants
Enrollment target

Study Summary

This is a randomized, double-blind, placebo-controlled, dose ranging pilot study to examine the effects of conivaptan in patients with acute decompensated heart failure.

Interventions

  • DRUG placebo
  • DRUG conivaptan

Trial Details

FieldValue
Enrollment Target 170 participants
Start Date 2002-11
Est. Completion 2004-03
Phase Phase 2
Cumberland Pharmaceuticals

43 total trials

What the finished NCT00057356 record still lists

NCT00057356 is an interventional study that assigns participants to a tested intervention. The registered 170 participants enrollment target is mid-sized for trials with a published cap, above the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (28% higher).

The record links to 0 conditions, and to 2 interventions - of which placebo is the first listed.

NCT00057356 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT00057356 about?

NCT00057356 is a clinical study titled "Safety and Efficacy Study of YM087 (Conivaptan) in Patients With Acute Decompensated Heart Failure". This is a randomized, double-blind, placebo-controlled, dose ranging pilot study to examine the effects of conivaptan in patients with acute decompensated heart failure.

What is the current status of trial NCT00057356?

This trial is currently completed. It is a Phase 2 study. The enrollment target is 170 participants. The study started on 2002-11. Estimated completion is 2004-03.

What interventions are being tested in trial NCT00057356?

The interventions under investigation include: placebo (DRUG), conivaptan (DRUG).

Who is sponsoring clinical trial NCT00057356?

This trial is sponsored by Cumberland Pharmaceuticals, which has 43 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT00057356's enrollment target sits among peer trials

170 399th of 2000 higher than 1,598 of 2,000 other Phase 2 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Phase 2 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

Nationwide trials with similar profiles

Cross-condition peers matched on enrollment target and registry start date, not the same-condition list above.

Similar enrollment target

  • NCT02016430 · 170 participants · NA

    Gut Flora Metabolite Reduction After Dietary Intervention (GRADY)

  • NCT02621021 · 170 participants · Phase 2

    A Phase 2 Trial for Metastatic Melanoma Using Adoptive Cell Therapy With Tumor Infiltrating Lymphocytes Plus IL-2 Either Alone or Following the Administration of Pembrolizumab

  • NCT04094701 · 170 participants · NA

    Hip Arthroscopy Postoperative Opioid Demands

  • NCT04166409 · 170 participants · Phase 3

    A Study of the Drugs Selumetinib vs. Carboplatin and Vincristine in Patients With Low-Grade Glioma

Similar registry start date

  • NCT05988463 · started 2027-01-01 · Phase 1

    Dose-Escalation Study of Artesunate Patients With IPF

  • NCT07219706 · started 2026-12-10 · NA

    Dietary Fiber and Time Restricted Eating

  • NCT02831335 · started 2026-12-01

    Technical Development of Multi-Parametric Renocerebral MRI

  • NCT05962346 · started 2026-12 · NA

    Fetal Endoscopic Tracheal Occlusion for Congenital Diaphragmatic Hernia

Source: ClinicalTrials.gov NCT00057356, the US trial registry maintained by the National Library of Medicine. NCT00057356 (mid enrollment · none site footprint · completed) retrieved and formatted by PlainTrial, see methodology.