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NCT00054444 · ClinicalTrials.gov registry record · Phase 1
Radiation Therapy and Chemotherapy in Treating Patients With Locally Advanced Cervical Cancer
A Phase 1 study, sponsored by Gynecologic Oncology Group.
- Completed
- Registry status
- Phase 1
- Development phase
- 11
- Enrollment target
NCT00054444: Completed Phase 1 study, sponsored by Gynecologic Oncology Group.
NCT00054444 is a Phase 1 study that has completed, run by Gynecologic Oncology Group. The registered enrollment target is 11 participants, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (82% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT00054444, a Phase 1 study, has completed, sponsored by Gynecologic Oncology Group.
- COMPLETED
- Registry status
- Phase 1
- Development phase
- 11 participants
- Enrollment target
Study Summary
This phase I trial is studying the side effects and best way to give radiation therapy when given together with topotecan and cisplatin in treating patients with locally advanced cervical cancer. This trial is also studying the best dose of topotecan when given in this regimen. Radiation therapy uses high-energy x-rays to damage tumor cells. Drugs used in chemotherapy, such as topotecan and cisplatin, use different ways to stop tumor cells from dividing so they stop growing or die. Combining radiation therapy with chemotherapy may kill more tumor cells.
Interventions
- DRUG Cisplatin
- RADIATION 3-Dimensional Conformal Radiation Therapy
- DRUG Topotecan Hydrochloride Liposomes
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 11 participants |
| Start Date | 2007-09 |
| Phase | Phase 1 |
What the finished NCT00054444 record still lists
NCT00054444 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 11 participants, a relatively small participant target, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (82% lower).
The record links to 0 conditions, and to 3 interventions - of which Cisplatin is the first listed.
NCT00054444 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT00054444 about?
NCT00054444 is a clinical study titled "Radiation Therapy and Chemotherapy in Treating Patients With Locally Advanced Cervical Cancer". This phase I trial is studying the side effects and best way to give radiation therapy when given together with topotecan and cisplatin in treating patients with locally advanced cervical cancer. This trial is also studying the best dose of topotecan when given in this regimen. Radiation therapy use...
What is the current status of trial NCT00054444?
This trial is currently completed. It is a Phase 1 study. The enrollment target is 11 participants. The study started on 2007-09.
What interventions are being tested in trial NCT00054444?
The interventions under investigation include: Cisplatin (DRUG), 3-Dimensional Conformal Radiation Therapy (RADIATION), Topotecan Hydrochloride Liposomes (DRUG).
Who is sponsoring clinical trial NCT00054444?
This trial is sponsored by Gynecologic Oncology Group, which has 154 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT00054444's enrollment target sits among peer trials
11 1911th of 2000 higher than 88 of 2,000 other Phase 1 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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