Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.

NCT00049296 · ClinicalTrials.gov registry record · Phase 1

Thalidomide and Docetaxel in Treating Patients With Advanced Cancer

A Phase 1 study, sponsored by Case Comprehensive Cancer Center.

Completed
Registry status
Phase 1
Development phase
26
Enrollment target

NCT00049296: Completed Phase 1 study, sponsored by Case Comprehensive Cancer Center.

NCT00049296 is a Phase 1 study that has completed, run by Case Comprehensive Cancer Center. The registered enrollment target is 26 participants, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (57% lower). According to ClinicalTrials.gov, the official US trial registry.

View on ClinicalTrials.gov ↗

View your shortlist →

The verdict

NCT00049296, a Phase 1 study, has completed, sponsored by Case Comprehensive Cancer Center.

COMPLETED
Registry status
Phase 1
Development phase
26 participants
Enrollment target

Study Summary

RATIONALE: Thalidomide may stop the growth of cancer by stopping blood flow to the tumor. Drugs used in chemotherapy use different ways to stop cancer cells from dividing so they stop growing or die. Combining thalidomide with docetaxel may kill more tumor cells. PURPOSE: Phase I trial to study the effectiveness of combining thalidomide with docetaxel in treating patients who have advanced cancer.

Interventions

  • DRUG docetaxel
  • DRUG thalidomide

Trial Details

FieldValue
Enrollment Target 26 participants
Start Date 2002-07
Est. Completion 2006-01
Phase Phase 1
Case Comprehensive Cancer Center

407 total trials

What the finished NCT00049296 record still lists

NCT00049296 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 26 participants, a relatively small participant target, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (57% lower).

The record links to 0 conditions, and to 2 interventions - of which docetaxel is the first listed.

NCT00049296 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT00049296 about?

NCT00049296 is a clinical study titled "Thalidomide and Docetaxel in Treating Patients With Advanced Cancer". RATIONALE: Thalidomide may stop the growth of cancer by stopping blood flow to the tumor. Drugs used in chemotherapy use different ways to stop cancer cells from dividing so they stop growing or die. Combining thalidomide with docetaxel may kill more tumor cells. PURPOSE: Phase I trial to study the...

What is the current status of trial NCT00049296?

This trial is currently completed. It is a Phase 1 study. The enrollment target is 26 participants. The study started on 2002-07. Estimated completion is 2006-01.

What interventions are being tested in trial NCT00049296?

The interventions under investigation include: docetaxel (DRUG), thalidomide (DRUG).

Who is sponsoring clinical trial NCT00049296?

This trial is sponsored by Case Comprehensive Cancer Center, which has 407 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT00049296's enrollment target sits among peer trials

26 1482nd of 2000 higher than 506 of 2,000 other Phase 1 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

Nationwide trials with similar profiles

Cross-condition peers matched on enrollment target and registry start date, not the same-condition list above.

Similar enrollment target

  • NCT02646475 · 26 participants · Phase 1

    Metabolic Effects of Angiotensin-(1-7)

  • NCT03603223 · 26 participants · Phase 2

    Pembrolizumab in Treating Participants With Leukoplakia

  • NCT04063592 · 26 participants · NA

    AMI Construction in Lower Extremity Residual Limbs

  • NCT04906460 · 26 participants · Phase 1

    Open-label Study of WVE-N531 in Patients With Duchenne Muscular Dystrophy (FORWARD-53)

Similar registry start date

  • NCT05988463 · started 2027-01-01 · Phase 1

    Dose-Escalation Study of Artesunate Patients With IPF

  • NCT07219706 · started 2026-12-10 · NA

    Dietary Fiber and Time Restricted Eating

  • NCT02831335 · started 2026-12-01

    Technical Development of Multi-Parametric Renocerebral MRI

  • NCT05962346 · started 2026-12 · NA

    Fetal Endoscopic Tracheal Occlusion for Congenital Diaphragmatic Hernia

Source: ClinicalTrials.gov NCT00049296, the US trial registry maintained by the National Library of Medicine. NCT00049296 (small enrollment · none site footprint · completed) retrieved and formatted by PlainTrial, see methodology.