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NCT00042224 · ClinicalTrials.gov registry record · Phase 1
Electroconvulsive Therapy in Clozapine Refractory Schizophrenia
A Phase 1 study of Schizophrenia, sponsored by Northwell Health.
- Completed
- Registry status
- Phase 1
- Development phase
- 39
- Enrollment target
- 1
- Study location
NCT00042224: Completed Phase 1 study of Schizophrenia, sponsored by Northwell Health.
NCT00042224 is a Phase 1 study of Schizophrenia that has completed, run by Northwell Health. The registered enrollment target is 39 participants, below the 219-participant average among 315 other Schizophrenia trials with a reported enrollment target (82% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT00042224, a Phase 1 study of Schizophrenia, has completed, sponsored by Northwell Health.
- COMPLETED
- Registry status
- Phase 1
- Development phase
- 39 participants
- Enrollment target
- 1
- Study location
Study Summary
This study will evaluate electroconvulsive therapy (ECT) in patients who have not responded adequately to clozapine.
Primary Outcome
Response is defined as 40% reduction of symptoms in the psychotic symptom sub-scale (hallucinatory behavior, suspiciousness, conceptual disorganization, and unusual thought of content) of the Brief Psychiatric Rating Scale (BPRS) at the end of the 8-week study. BPRS assesses psychotic symptoms on a 18-item scale. The severity of each item is rated on a continuous scale from 1-7, with 1 being the least severe and 7 being most severe. Participants included in the study, at baseline had at least a
Conditions Studied
Interventions
- DRUG Clozapine
- PROCEDURE Electroconvulsive Therapy (ECT)
Study Locations (1)
New York
- Zucker Hillside Hospital - Glen Oaks
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 39 participants |
| Start Date | 2000-12 |
| Est. Completion | 2008-07 |
| Phase | Phase 1 |
What the finished NCT00042224 record still lists
NCT00042224 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 39 participants, a relatively small participant target, below the 219-participant average among 315 other Schizophrenia trials with a reported enrollment target (82% lower).
The record links to 1 condition, with Schizophrenia appearing as the primary indexed condition, and to 2 interventions - of which Clozapine is the first listed.
NCT00042224 reports a single indexed study location in New York.
Frequently Asked Questions
What is clinical trial NCT00042224 about?
NCT00042224 is a clinical study titled "Electroconvulsive Therapy in Clozapine Refractory Schizophrenia". This study will evaluate electroconvulsive therapy (ECT) in patients who have not responded adequately to clozapine.
What is the current status of trial NCT00042224?
This trial is currently completed. It is a Phase 1 study. The enrollment target is 39 participants. The study started on 2000-12. Estimated completion is 2008-07.
What conditions does trial NCT00042224 study?
This clinical trial studies the following conditions: Schizophrenia.
What interventions are being tested in trial NCT00042224?
The interventions under investigation include: Clozapine (DRUG), Electroconvulsive Therapy (ECT) (PROCEDURE).
Who is sponsoring clinical trial NCT00042224?
This trial is sponsored by Northwell Health, which has 370 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT00042224 being conducted?
This trial has 1 study location across New York. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
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Where NCT00042224's enrollment target sits among peer trials
39 244th of 315 higher than 71 of 315 other Schizophrenia trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Schizophrenia trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
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