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NCT00041548 · ClinicalTrials.gov registry record · Phase 1
Inhaled Nitric Oxide in Neonates With Elevated A-a DO2 Gradients Not Requiring Mechanical Ventilation
A Phase 1 study, sponsored by Mallinckrodt.
- Terminated
- Registry status
- Phase 1
- Development phase
- 7
- Enrollment target
NCT00041548: Clinical Trial Phase 1 study, sponsored by Mallinckrodt.
NCT00041548 is a Phase 1 study that was terminated before completion, run by Mallinckrodt. The registered enrollment target is 7 participants, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (88% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT00041548, a Phase 1 study, was terminated before completion, sponsored by Mallinckrodt.
- TERMINATED
- Registry status
- Phase 1
- Development phase
- 7 participants
- Enrollment target
Study Summary
The purpose of this pilot study is to evaluate whether administration of nitric oxide (NO)gas by oxygen hood at 20 ppm significantly increases PaO2, as compared to placebo gas (oxygen), within one hour of initiation and with no significant adverse effects.
Interventions
- DRUG Oxygen
- DRUG nitric oxide for inhalation
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 7 participants |
| Start Date | 2002-05 |
| Est. Completion | 2005-06 |
| Phase | Phase 1 |
Why NCT00041548 stopped before completion
NCT00041548 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 7 participants, a relatively small participant target, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (88% lower).
The record links to 0 conditions, and to 2 interventions - of which Oxygen is the first listed.
NCT00041548 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT00041548 about?
NCT00041548 is a clinical study titled "Inhaled Nitric Oxide in Neonates With Elevated A-a DO2 Gradients Not Requiring Mechanical Ventilation". The purpose of this pilot study is to evaluate whether administration of nitric oxide (NO)gas by oxygen hood at 20 ppm significantly increases PaO2, as compared to placebo gas (oxygen), within one hour of initiation and with no significant adverse effects.
What is the current status of trial NCT00041548?
This trial is currently terminated. It is a Phase 1 study. The enrollment target is 7 participants. The study started on 2002-05. Estimated completion is 2005-06.
What interventions are being tested in trial NCT00041548?
The interventions under investigation include: Oxygen (DRUG), nitric oxide for inhalation (DRUG).
Who is sponsoring clinical trial NCT00041548?
This trial is sponsored by Mallinckrodt, which has 69 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT00041548's enrollment target sits among peer trials
7 1972nd of 2000 higher than 27 of 2,000 other Phase 1 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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