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NCT00027443 · ClinicalTrials.gov registry record · NA
Study of Muromonab-CD3 and Cyclosporine in Patients With Giant Cell Myocarditis
A NA study, sponsored by Mayo Clinic.
- Completed
- Registry status
- NA
- Development phase
- 40
- Enrollment target
NCT00027443: Completed NA study, sponsored by Mayo Clinic.
NCT00027443 is a NA study that has completed, run by Mayo Clinic. The registered enrollment target is 40 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (97% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT00027443, a NA study, has completed, sponsored by Mayo Clinic.
- COMPLETED
- Registry status
- NA
- Development phase
- 40 participants
- Enrollment target
Study Summary
This is a study to determine the efficacy of muromonab-CD3 and cyclosporine as treatment in patients with giant cell myocarditis (GCM). T lymphocytes appear to be involved in GCM. Muromonab-CD3 has been shown to reduce the number of lymphocytes and cyclosporine inhibits lymphocyte activation. This treatment may prolong patient survival until transplantation or ventricular assist device placement is possible.
Interventions
- DRUG Cyclosporine
- DRUG Muromonab-CD3
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 40 participants |
| Start Date | 2001-08 |
| Est. Completion | 2007-07 |
| Phase | NA |
What the finished NCT00027443 record still lists
NCT00027443 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 40 participants, a relatively small participant target, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (97% lower).
The record links to 0 conditions, and to 2 interventions - of which Cyclosporine is the first listed.
NCT00027443 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT00027443 about?
NCT00027443 is a clinical study titled "Study of Muromonab-CD3 and Cyclosporine in Patients With Giant Cell Myocarditis". This is a study to determine the efficacy of muromonab-CD3 and cyclosporine as treatment in patients with giant cell myocarditis (GCM). T lymphocytes appear to be involved in GCM. Muromonab-CD3 has been shown to reduce the number of lymphocytes and cyclosporine inhibits lymphocyte activation. This t...
What is the current status of trial NCT00027443?
This trial is currently completed. It is a NA study. The enrollment target is 40 participants. The study started on 2001-08. Estimated completion is 2007-07.
What interventions are being tested in trial NCT00027443?
The interventions under investigation include: Cyclosporine (DRUG), Muromonab-CD3 (DRUG).
Who is sponsoring clinical trial NCT00027443?
This trial is sponsored by Mayo Clinic, which has 2,844 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT00027443's enrollment target sits among peer trials
40 1447th of 2000 higher than 465 of 2,000 other NA trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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