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NCT00026104 · ClinicalTrials.gov registry record · Phase 2
Combination Chemotherapy Plus Radiation Therapy With or Without Tipifarnib in Treating Patients With Locally Advanced Pancreatic Cancer
A Phase 2 study, sponsored by National Cancer Institute (NCI).
- Completed
- Registry status
- Phase 2
- Development phase
- 154
- Enrollment target
NCT00026104: Completed Phase 2 study, sponsored by National Cancer Institute (NCI).
NCT00026104 is a Phase 2 study that has completed, run by National Cancer Institute (NCI). The registered enrollment target is 154 participants, above the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (16% higher). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT00026104, a Phase 2 study, has completed, sponsored by National Cancer Institute (NCI).
- COMPLETED
- Registry status
- Phase 2
- Development phase
- 154 participants
- Enrollment target
Study Summary
Randomized phase II trial to compare the effectiveness of gemcitabine, paclitaxel, and radiation therapy with or without tipifarnib in treating patients who have locally advanced pancreatic cancer. Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. Radiation therapy uses high-energy x-rays to damage tumor cells. Tipifarnib may stop the growth of tumor cells by blocking the enzymes necessary for tumor cell growth. Combining chemotherapy and radiation therapy with tipifarnib may be an effective treatment for pancreatic cancer.
Primary Outcome
Calculated along with associated 95% confidence intervals.
Interventions
- DRUG paclitaxel
- RADIATION radiation therapy
- DRUG gemcitabine hydrochloride
- DRUG tipifarnib
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 154 participants |
| Start Date | 2001-11 |
| Phase | Phase 2 |
What the finished NCT00026104 record still lists
NCT00026104 is an interventional study that assigns participants to a tested intervention. The registered 154 participants enrollment target is mid-sized for trials with a published cap, above the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (16% higher).
The record links to 0 conditions, and to 4 interventions - of which paclitaxel is the first listed.
NCT00026104 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT00026104 about?
NCT00026104 is a clinical study titled "Combination Chemotherapy Plus Radiation Therapy With or Without Tipifarnib in Treating Patients With Locally Advanced Pancreatic Cancer". Randomized phase II trial to compare the effectiveness of gemcitabine, paclitaxel, and radiation therapy with or without tipifarnib in treating patients who have locally advanced pancreatic cancer. Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing o...
What is the current status of trial NCT00026104?
This trial is currently completed. It is a Phase 2 study. The enrollment target is 154 participants. The study started on 2001-11.
What interventions are being tested in trial NCT00026104?
The interventions under investigation include: paclitaxel (DRUG), radiation therapy (RADIATION), gemcitabine hydrochloride (DRUG), tipifarnib (DRUG).
Who is sponsoring clinical trial NCT00026104?
This trial is sponsored by National Cancer Institute (NCI), which has 3,257 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT00026104's enrollment target sits among peer trials
154 448th of 2000 higher than 1,552 of 2,000 other Phase 2 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 2 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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