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NCT00026013 · ClinicalTrials.gov registry record · NA

Effects of St. John's Wort on the Effectiveness of Oral Contraceptives

A NA study, sponsored by National Center for Complementary and Integrative Health (NCCIH).

Completed
Registry status
NA
Development phase
25
Enrollment target

NCT00026013: Completed NA study, sponsored by National Center for Complementary and Integrative Health (NCCIH).

NCT00026013 is a NA study that has completed, run by National Center for Complementary and Integrative Health (NCCIH). The registered enrollment target is 25 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (98% lower). According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT00026013, a NA study, has completed, sponsored by National Center for Complementary and Integrative Health (NCCIH).

COMPLETED
Registry status
NA
Development phase
25 participants
Enrollment target

Study Summary

The purpose of this study is to evaluate the effects of a common herbal remedy, St. John's Wort, on the effectiveness of birth control pills. St. John's Wort has recently been shown to increase metabolism of some drugs. If it could increase metabolism of oral contraceptives as well, it may increase the risk of contraceptive failure and unintended pregnancy. Study participants will be evaluated for risk of ovulation on oral contraceptives before and during simultaneous therapy with St. John's Wort.

Interventions

  • DRUG hypericum perforatum

Trial Details

FieldValue
Enrollment Target 25 participants
Start Date 2002-01
Est. Completion 2004-01
Phase NA

What the finished NCT00026013 record still lists

NCT00026013 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 25 participants, a relatively small participant target, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (98% lower).

The record links to 0 conditions, and to 1 intervention - of which hypericum perforatum is the first listed.

NCT00026013 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT00026013 about?

NCT00026013 is a clinical study titled "Effects of St. John's Wort on the Effectiveness of Oral Contraceptives". The purpose of this study is to evaluate the effects of a common herbal remedy, St. John's Wort, on the effectiveness of birth control pills. St. John's Wort has recently been shown to increase metabolism of some drugs. If it could increase metabolism of oral contraceptives as well, it may increase ...

What is the current status of trial NCT00026013?

This trial is currently completed. It is a NA study. The enrollment target is 25 participants. The study started on 2002-01. Estimated completion is 2004-01.

What interventions are being tested in trial NCT00026013?

The interventions under investigation include: hypericum perforatum (DRUG).

Who is sponsoring clinical trial NCT00026013?

This trial is sponsored by National Center for Complementary and Integrative Health (NCCIH), which has 203 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT00026013's enrollment target sits among peer trials

25 1712th of 2000 higher than 265 of 2,000 other NA trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT00026013, the US trial registry maintained by the National Library of Medicine. NCT00026013 (small enrollment · none site footprint · completed) retrieved and formatted by PlainTrial, see methodology.