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NCT00023049 · ClinicalTrials.gov registry record
Genetic Analysis of Hereditary Disorders of Hearing and Balance
A clinical trial, sponsored by National Institute on Deafness and Other Communication Disorders (NIDCD).
- Completed
- Registry status
- 335
- Enrollment target
NCT00023049: Completed study, sponsored by National Institute on Deafness and Other Communication Disorders (NIDCD).
NCT00023049 is a clinical trial that has completed, run by National Institute on Deafness and Other Communication Disorders (NIDCD). The registered enrollment target is 335 participants. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT00023049 has completed, sponsored by National Institute on Deafness and Other Communication Disorders (NIDCD).
- COMPLETED
- Registry status
- 335 participants
- Enrollment target
Study Summary
This study will try to identify the genetic causes of hereditary hearing loss or balance disorders. People with a hearing or balance disorder that affects more than one family member may be eligible for this study. They and their immediate family members may undergo some or all of the following procedures: * Medical and family history, including questions about hearing, balance and other ear-related issues, and review of medical records. * Routine physical examination. * Blood draw or buccal swab (brushing inside the cheek to collect cells) - Tissue is collected for DNA analysis to look for changes in genes that may be related to hearing loss. * Hearing tests - The subject listens for tones emitted through a small earphone. * Balance tests to see if balance functions of the inner ear are associated with the hearing loss In one test the subject wears goggles and watches moving lights while cold or warm air is blown into the ears. A second test involves sitting in a spinning chair in a quiet, dark room. * Photograph - A photograph may be taken as a record of eye shape and color, distance between the eyes, and hair color. * Computed tomography (CT) and magnetic resonance imaging (MRI) scans - These tests show the structure of the inner ear. For CT, the subject lies still for a short time while X-ray images are obtained. For MRI, the patient lies on a stretcher that is moved into a cylindrical machine with a strong magnetic field. The magnetic field and radio waves produce images of the inner ear. The radio waves cause loud thumping noises that can be muffled by the use of earplugs.
Primary Outcome
Characterize the natural history of hereditary disorders affecting hearing and/or balance Identify the genes, including both known and as yet undiscovered genes, that can cause hereditary disorders of hearing or balance Identify and characterize the structure and functions of these genes in the development and function of the peripheral auditory and vestibular systems Determine how mutations in these genes cause hearing loss and vestibular dysfunction Correlate genotypes and phenotypes to identi
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 335 participants |
| Start Date | 2002-12-23 |
What the finished NCT00023049 record still lists
NCT00023049 is an observational study that tracks outcomes without assigning an intervention. The registered 335 participants enrollment target is mid-sized for trials with a published cap.
The record links to 0 conditions, and to 0 interventions.
NCT00023049 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT00023049 about?
NCT00023049 is a clinical study titled "Genetic Analysis of Hereditary Disorders of Hearing and Balance". This study will try to identify the genetic causes of hereditary hearing loss or balance disorders. People with a hearing or balance disorder that affects more than one family member may be eligible for this study. They and their immediate family members may undergo some or all of the following pro...
What is the current status of trial NCT00023049?
This trial is currently completed. The enrollment target is 335 participants. The study started on 2002-12-23.
Who is sponsoring clinical trial NCT00023049?
This trial is sponsored by National Institute on Deafness and Other Communication Disorders (NIDCD), which has 34 total clinical trials registered on ClinicalTrials.gov.
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