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NCT00020722 · ClinicalTrials.gov registry record · Phase 2

Chemotherapy Followed by Peripheral Stem Cell Transplantation Plus Biological Therapy in Treating Women With Stage IV Breast Cancer

A Phase 2 study, sponsored by Barbara Ann Karmanos Cancer Institute.

Terminated
Registry status
Phase 2
Development phase
7
Enrollment target

NCT00020722: Clinical Trial Phase 2 study, sponsored by Barbara Ann Karmanos Cancer Institute.

NCT00020722 is a Phase 2 study that was terminated before completion, run by Barbara Ann Karmanos Cancer Institute. The registered enrollment target is 7 participants, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (95% lower). According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT00020722, a Phase 2 study, was terminated before completion, sponsored by Barbara Ann Karmanos Cancer Institute.

TERMINATED
Registry status
Phase 2
Development phase
7 participants
Enrollment target

Study Summary

RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. Combining chemotherapy with peripheral stem cell transplantation plus biological therapy may allow the doctor to give higher doses of chemotherapy drugs and kill more tumor cells. PURPOSE: This phase II trial is studying how well chemotherapy followed by peripheral stem cell transplantation plus biological therapy works in treating women with stage IV breast cancer.

Interventions

  • PROCEDURE Leukapheresis
  • BIOLOGICAL therapeutic autologous lymphocytes
  • DRUG Ifosfamide, carboplatin, and etoposide (ICE) regimen
  • DRUG Cyclophosphamide, Thiotepa, Carboplatin (CTC) or STAMP V (CTC)
  • PROCEDURE peripheral blood stem cell transplantation (PBSCT)

Trial Details

FieldValue
Enrollment Target 7 participants
Start Date 2007-08
Est. Completion 2013-03
Phase Phase 2

Why NCT00020722 stopped before completion

NCT00020722 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 7 participants, a relatively small participant target, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (95% lower).

The record links to 0 conditions, and to 5 interventions - of which Leukapheresis is the first listed.

NCT00020722 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT00020722 about?

NCT00020722 is a clinical study titled "Chemotherapy Followed by Peripheral Stem Cell Transplantation Plus Biological Therapy in Treating Women With Stage IV Breast Cancer". RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. Combining chemotherapy with peripheral stem cell transplantation plus biological therapy may allow the doctor to give higher doses of chemotherapy drugs and kill more tumor cells. ...

What is the current status of trial NCT00020722?

This trial is currently terminated. It is a Phase 2 study. The enrollment target is 7 participants. The study started on 2007-08. Estimated completion is 2013-03.

What interventions are being tested in trial NCT00020722?

The interventions under investigation include: Leukapheresis (PROCEDURE), therapeutic autologous lymphocytes (BIOLOGICAL), Ifosfamide, carboplatin, and etoposide (ICE) regimen (DRUG), Cyclophosphamide, Thiotepa, Carboplatin (CTC) or STAMP V (CTC) (DRUG), peripheral blood stem cell transplantation (PBSCT) (PROCEDURE).

Who is sponsoring clinical trial NCT00020722?

This trial is sponsored by Barbara Ann Karmanos Cancer Institute, which has 139 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT00020722's enrollment target sits among peer trials

7 1996th of 2000 higher than 5 of 2,000 other Phase 2 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Phase 2 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT00020722, the US trial registry maintained by the National Library of Medicine. NCT00020722 (small enrollment · none site footprint · terminated) retrieved and formatted by PlainTrial, see methodology.