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NCT00007852 · ClinicalTrials.gov registry record · Phase 2

Rituximab & Combination Chemotherapy Followed by Transplantation in Relapsed or Refractory Non-Hodgkin's Lymphoma

A Phase 2 study, sponsored by University of Nebraska.

Completed
Registry status
Phase 2
Development phase
44
Enrollment target

NCT00007852 is a Phase 2 study that has completed, run by University of Nebraska. The registered enrollment target is 44 participants.

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The verdict

NCT00007852, a Phase 2 study, has completed, sponsored by University of Nebraska.

COMPLETED
Registry status
Phase 2
Development phase
44 participants
Enrollment target

Study Summary

RATIONALE: Monoclonal antibodies such as rituximab can locate cancer cells and either kill them or deliver cancer-killing substances to them without harming normal cells. Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. Combining chemotherapy with peripheral stem cell transplantation or bone marrow transplantation may allow the doctor to give higher doses of chemotherapy drugs and kill more tumor cells. PURPOSE: Phase II trial to study the effectiveness of rituximab and combination chemotherapy followed by bone marrow or peripheral stem cell transplantation in treating patients who have relapsed or refractory non-Hodgkin's lymphoma.

Interventions

  • BIOLOGICAL rituximab
  • DRUG etoposide
  • DRUG melphalan
  • DRUG carmustine
  • DRUG cytarabine

Trial Details

FieldValue
Enrollment Target 44 participants
Start Date 2000-09-01
Est. Completion 2011-01-01
Phase Phase 2

Sponsor

University of Nebraska

407 total trials

What the Registry Record Tells You About NCT00007852

The ClinicalTrials.gov registry entry for NCT00007852 describes a study currently listed as completed, categorized as Phase 2. The registered enrollment target is 44 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is University of Nebraska, which has 407 total studies on file at ClinicalTrials.gov.

The record links to 0 conditions, and to 5 interventions - of which rituximab is the first listed.

NCT00007852 reports 0 study locations.

Frequently Asked Questions

What is clinical trial NCT00007852 about?

NCT00007852 is a clinical study titled "Rituximab & Combination Chemotherapy Followed by Transplantation in Relapsed or Refractory Non-Hodgkin's Lymphoma". RATIONALE: Monoclonal antibodies such as rituximab can locate cancer cells and either kill them or deliver cancer-killing substances to them without harming normal cells. Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. Combining chemothera...

What is the current status of trial NCT00007852?

This trial is currently completed. It is a Phase 2 study. The enrollment target is 44 participants. The study started on 2000-09-01. Estimated completion is 2011-01-01.

What interventions are being tested in trial NCT00007852?

The interventions under investigation include: rituximab (BIOLOGICAL), etoposide (DRUG), melphalan (DRUG), carmustine (DRUG), cytarabine (DRUG).

Who is sponsoring clinical trial NCT00007852?

This trial is sponsored by University of Nebraska, which has 407 total clinical trials registered on ClinicalTrials.gov.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.