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NCT00006461 · ClinicalTrials.gov registry record · Phase 3
Combination Chemotherapy Followed by Second-Look Surgery and Radiation Therapy in Treating Children With Nonmetastatic Medulloblastoma or Primitive Neuroectodermal Tumor
A Phase 3 study, sponsored by Children's Oncology Group.
- Completed
- Registry status
- Phase 3
- Development phase
- 82
- Enrollment target
NCT00006461: Completed Phase 3 study, sponsored by Children's Oncology Group.
NCT00006461 is a Phase 3 study that has completed, run by Children's Oncology Group. The registered enrollment target is 82 participants, below the 772-participant average among 15,282 other Phase 3 trials with a reported enrollment target (89% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT00006461, a Phase 3 study, has completed, sponsored by Children's Oncology Group.
- COMPLETED
- Registry status
- Phase 3
- Development phase
- 82 participants
- Enrollment target
Study Summary
This phase III trial is studying how well combination chemotherapy followed by second-look surgery and radiation therapy works in treating children with nonmetastatic medulloblastoma or primitive neuroectodermal tumor. Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. Radiation therapy uses high-energy x-rays to damage tumor cells. Combining more than one drug and combining chemotherapy with surgery and radiation therapy may kill more tumor cells.
Interventions
- DRUG cisplatin
- DRUG cyclophosphamide
- PROCEDURE therapeutic conventional surgery
- DRUG etoposide
- DRUG vincristine sulfate
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 82 participants |
| Start Date | 2000-10 |
| Phase | Phase 3 |
What the finished NCT00006461 record still lists
NCT00006461 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 82 participants, a relatively small participant target, below the 772-participant average among 15,282 other Phase 3 trials with a reported enrollment target (89% lower).
The record links to 0 conditions, and to 5 interventions - of which cisplatin is the first listed.
NCT00006461 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT00006461 about?
NCT00006461 is a clinical study titled "Combination Chemotherapy Followed by Second-Look Surgery and Radiation Therapy in Treating Children With Nonmetastatic Medulloblastoma or Primitive Neuroectodermal Tumor". This phase III trial is studying how well combination chemotherapy followed by second-look surgery and radiation therapy works in treating children with nonmetastatic medulloblastoma or primitive neuroectodermal tumor. Drugs used in chemotherapy use different ways to stop tumor cells from dividing s...
What is the current status of trial NCT00006461?
This trial is currently completed. It is a Phase 3 study. The enrollment target is 82 participants. The study started on 2000-10.
What interventions are being tested in trial NCT00006461?
The interventions under investigation include: cisplatin (DRUG), cyclophosphamide (DRUG), therapeutic conventional surgery (PROCEDURE), etoposide (DRUG), vincristine sulfate (DRUG).
Who is sponsoring clinical trial NCT00006461?
This trial is sponsored by Children's Oncology Group, which has 342 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT00006461's enrollment target sits among peer trials
82 1752nd of 2000 higher than 249 of 2,000 other Phase 3 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 3 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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