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NCT00005919 · ClinicalTrials.gov registry record
Cause of Pigment Dispersion Syndrome
A clinical trial, sponsored by National Eye Institute (NEI).
- Completed
- Registry status
- 90
- Enrollment target
NCT00005919 is a clinical trial that has completed, run by National Eye Institute (NEI). The registered enrollment target is 90 participants.
The verdict
NCT00005919 has completed, sponsored by National Eye Institute (NEI).
- COMPLETED
- Registry status
- 90 participants
- Enrollment target
Study Summary
The purpose of this study is to learn how pigment is released from the iris (the colored part of the eye) in patients with pigment dispersion syndrome. It will do this by examining the response of the pupil (the central opening of the iris) to a flash of light to determine what is happening in the iris to cause release of the pigment. In pigment dispersion syndrome, pigment released from the iris is deposited in other parts of the eye, including the trabecular meshwork-a filter-like tissue in the front of the eye. Aqueous fluid (fluid continuously produced by the eye) normally flows out of the eye through the trabecular meshwork. In some patients, the pigment deposits may block tiny holes in the meshwork, preventing the fluid from flowing out. This can cause an increase in eye pressure that may lead to glaucoma and some loss of vision. Understanding how pigment is released from the iris may help predict the course of pigment dispersion syndrome and identify which patients will likely develop increased eye pressure. Patients with pigment dispersion syndrome and normal volunteers may be eligible for this study. All participants will have the following procedures, which will be completed in two clinic visits: First visit 1. Examination of the front of the eyes, including the cornea, iris and lens. 2. Vision testing and measurements of visual field and eye pressure. 3. Examination of the trabecular meshwork. For this test, a contact lens is placed on the eye after the eye has been numbed with anesthetic drops. Second visit 1. Refraction (dilation of the pupils with drops) and examination of the back of the eyes, including the optic nerve. 2. Reaction of the pupils to low-level infrared light (pupillography). During this 15-minute test, the patient or volunteer wears a lightweight headband with two small cameras mounted on it. The cameras-one which views the eye and the other the subject's field of view-record pupil dilation and position. The test results in patie
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 90 participants |
| Start Date | 2000-06 |
| Est. Completion | 2003-08 |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT00005919
The ClinicalTrials.gov registry entry for NCT00005919 describes a study currently listed as completed, categorized as an unspecified phase. The registered enrollment target is 90 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is National Eye Institute (NEI), which has 221 total studies on file at ClinicalTrials.gov.
The record links to 0 conditions, and to 0 interventions.
NCT00005919 reports 0 study locations.
Frequently Asked Questions
What is clinical trial NCT00005919 about?
NCT00005919 is a clinical study titled "Cause of Pigment Dispersion Syndrome". The purpose of this study is to learn how pigment is released from the iris (the colored part of the eye) in patients with pigment dispersion syndrome. It will do this by examining the response of the pupil (the central opening of the iris) to a flash of light to determine what is happening in the i...
What is the current status of trial NCT00005919?
This trial is currently completed. The enrollment target is 90 participants. The study started on 2000-06. Estimated completion is 2003-08.
Who is sponsoring clinical trial NCT00005919?
This trial is sponsored by National Eye Institute (NEI), which has 221 total clinical trials registered on ClinicalTrials.gov.
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