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NCT00005812 · ClinicalTrials.gov registry record · Phase 2
Temozolomide in Treating Patients With Leptomeningeal Metastases From a Solid Tumor or Lymphoma
A Phase 2 study, sponsored by Dartmouth-Hitchcock Medical Center.
- Terminated
- Registry status
- Phase 2
- Development phase
- 12
- Enrollment target
NCT00005812: Clinical Trial Phase 2 study, sponsored by Dartmouth-Hitchcock Medical Center.
NCT00005812 is a Phase 2 study that was terminated before completion, run by Dartmouth-Hitchcock Medical Center. The registered enrollment target is 12 participants, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (91% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT00005812, a Phase 2 study, was terminated before completion, sponsored by Dartmouth-Hitchcock Medical Center.
- TERMINATED
- Registry status
- Phase 2
- Development phase
- 12 participants
- Enrollment target
Study Summary
RATIONALE: Drugs used in chemotherapy use different ways to stop cancer cells from dividing so they stop growing or die. PURPOSE: Phase II trial to study the effectiveness of temozolomide in treating patients who have leptomeningeal metastases from a solid tumor or lymphoma.
Primary Outcome
Response will be assessed clinically, cytologically, and radiographically.
Interventions
- DRUG temozolomide
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 12 participants |
| Start Date | 2000-01 |
| Est. Completion | 2004-05 |
| Phase | Phase 2 |
Why NCT00005812 stopped before completion
NCT00005812 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 12 participants, a relatively small participant target, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (91% lower).
The record links to 0 conditions, and to 1 intervention - of which temozolomide is the first listed.
NCT00005812 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT00005812 about?
NCT00005812 is a clinical study titled "Temozolomide in Treating Patients With Leptomeningeal Metastases From a Solid Tumor or Lymphoma". RATIONALE: Drugs used in chemotherapy use different ways to stop cancer cells from dividing so they stop growing or die. PURPOSE: Phase II trial to study the effectiveness of temozolomide in treating patients who have leptomeningeal metastases from a solid tumor or lymphoma.
What is the current status of trial NCT00005812?
This trial is currently terminated. It is a Phase 2 study. The enrollment target is 12 participants. The study started on 2000-01. Estimated completion is 2004-05.
What interventions are being tested in trial NCT00005812?
The interventions under investigation include: temozolomide (DRUG).
Who is sponsoring clinical trial NCT00005812?
This trial is sponsored by Dartmouth-Hitchcock Medical Center, which has 427 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT00005812's enrollment target sits among peer trials
12 1948th of 2000 higher than 34 of 2,000 other Phase 2 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 2 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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