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NCT00005800 · ClinicalTrials.gov registry record · Phase 2

Doxorubicin and Docetaxel in Treating Women With Stage III Breast Cancer

A Phase 2 study, sponsored by H. Lee Moffitt Cancer Center and Research Institute.

Completed
Registry status
Phase 2
Development phase
45
Enrollment target

NCT00005800: Completed Phase 2 study, sponsored by H. Lee Moffitt Cancer Center and Research Institute.

NCT00005800 is a Phase 2 study that has completed, run by H. Lee Moffitt Cancer Center and Research Institute. The registered enrollment target is 45 participants, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (66% lower). According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT00005800, a Phase 2 study, has completed, sponsored by H. Lee Moffitt Cancer Center and Research Institute.

COMPLETED
Registry status
Phase 2
Development phase
45 participants
Enrollment target

Study Summary

RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. Combining more than one drug may kill more tumor cells. PURPOSE: Phase II trial to study the effectiveness of doxorubicin and docetaxel in treating women who have stage III breast cancer.

Primary Outcome

Evaluate the pathological response rate of sequential doxorubicin and docetaxel chemotherapy in the neoadjuvant treatment of women with stage III breast cancer. Pathologic response is classified as either complete pathologic response or partial pathologic response based on the size of residual tumor after treatment (complete pathologic response if 0 cm, partial pathologic response if \>0 cm).

Interventions

  • DRUG Docetaxel
  • DRUG Doxorubicin
  • BIOLOGICAL Filgrastim
  • PROCEDURE Surgery

Trial Details

FieldValue
Enrollment Target 45 participants
Start Date 1999-04
Est. Completion 2012-05
Phase Phase 2

What the finished NCT00005800 record still lists

NCT00005800 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 45 participants, a relatively small participant target, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (66% lower).

The record links to 0 conditions, and to 4 interventions - of which Docetaxel is the first listed.

NCT00005800 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT00005800 about?

NCT00005800 is a clinical study titled "Doxorubicin and Docetaxel in Treating Women With Stage III Breast Cancer". RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. Combining more than one drug may kill more tumor cells. PURPOSE: Phase II trial to study the effectiveness of doxorubicin and docetaxel in treating women who have stage III breast...

What is the current status of trial NCT00005800?

This trial is currently completed. It is a Phase 2 study. The enrollment target is 45 participants. The study started on 1999-04. Estimated completion is 2012-05.

What interventions are being tested in trial NCT00005800?

The interventions under investigation include: Docetaxel (DRUG), Doxorubicin (DRUG), Filgrastim (BIOLOGICAL), Surgery (PROCEDURE).

Who is sponsoring clinical trial NCT00005800?

This trial is sponsored by H. Lee Moffitt Cancer Center and Research Institute, which has 502 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT00005800's enrollment target sits among peer trials

45 1296th of 2000 higher than 679 of 2,000 other Phase 2 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Phase 2 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT00005800, the US trial registry maintained by the National Library of Medicine. NCT00005800 (small enrollment · none site footprint · completed) retrieved and formatted by PlainTrial, see methodology.