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NCT00005612 · ClinicalTrials.gov registry record · Phase 1

Combination Chemotherapy Followed by Peripheral Stem Cell Transplantation in Treating Patients With Ovarian Epithelial Cancer

A Phase 1 study, sponsored by H. Lee Moffitt Cancer Center and Research Institute.

Terminated
Registry status
Phase 1
Development phase
3
Enrollment target

NCT00005612: Clinical Trial Phase 1 study, sponsored by H. Lee Moffitt Cancer Center and Research Institute.

NCT00005612 is a Phase 1 study that was terminated before completion, run by H. Lee Moffitt Cancer Center and Research Institute. The registered enrollment target is 3 participants, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (95% lower). According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT00005612, a Phase 1 study, was terminated before completion, sponsored by H. Lee Moffitt Cancer Center and Research Institute.

TERMINATED
Registry status
Phase 1
Development phase
3 participants
Enrollment target

Study Summary

RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. Combining chemotherapy with autologous peripheral stem cell transplantation may allow the doctor to give higher doses of chemotherapy drugs and kill more tumor cells. PURPOSE: Phase I/II trial to study the effectiveness of combination chemotherapy followed by peripheral stem cell transplantation in treating patients who have ovarian epithelial cancer.

Primary Outcome

Progression free survival is defined as the time from date of enrollment to the time of recurrence

Interventions

  • DRUG carboplatin
  • DRUG cyclophosphamide
  • DRUG paclitaxel
  • DRUG etoposide
  • BIOLOGICAL filgrastim

Trial Details

FieldValue
Enrollment Target 3 participants
Start Date 1999-08
Est. Completion 2004-02
Phase Phase 1

Why NCT00005612 stopped before completion

NCT00005612 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 3 participants, a relatively small participant target, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (95% lower).

The record links to 0 conditions, and to 5 interventions - of which carboplatin is the first listed.

NCT00005612 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT00005612 about?

NCT00005612 is a clinical study titled "Combination Chemotherapy Followed by Peripheral Stem Cell Transplantation in Treating Patients With Ovarian Epithelial Cancer". RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. Combining chemotherapy with autologous peripheral stem cell transplantation may allow the doctor to give higher doses of chemotherapy drugs and kill more tumor cells. PURPOSE: Pha...

What is the current status of trial NCT00005612?

This trial is currently terminated. It is a Phase 1 study. The enrollment target is 3 participants. The study started on 1999-08. Estimated completion is 2004-02.

What interventions are being tested in trial NCT00005612?

The interventions under investigation include: carboplatin (DRUG), cyclophosphamide (DRUG), paclitaxel (DRUG), etoposide (DRUG), filgrastim (BIOLOGICAL).

Who is sponsoring clinical trial NCT00005612?

This trial is sponsored by H. Lee Moffitt Cancer Center and Research Institute, which has 502 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT00005612's enrollment target sits among peer trials

3 1999th of 2000 higher than 1 of 2,000 other Phase 1 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT00005612, the US trial registry maintained by the National Library of Medicine. NCT00005612 (small enrollment · none site footprint · terminated) retrieved and formatted by PlainTrial, see methodology.