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NCT00005604 · ClinicalTrials.gov registry record · Phase 1

Interleukin-12 Plus Interleukin-2 in Treating Patients With Advanced Solid Tumors

A Phase 1 study, sponsored by National Cancer Institute (NCI).

Completed
Registry status
Phase 1
Development phase
25
Enrollment target

NCT00005604: Completed Phase 1 study, sponsored by National Cancer Institute (NCI).

NCT00005604 is a Phase 1 study that has completed, run by National Cancer Institute (NCI). The registered enrollment target is 25 participants, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (58% lower). According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT00005604, a Phase 1 study, has completed, sponsored by National Cancer Institute (NCI).

COMPLETED
Registry status
Phase 1
Development phase
25 participants
Enrollment target

Study Summary

Phase I trial to study the effectiveness of interleukin-12 plus interleukin-2 in treating patients who have advanced solid tumors. Interleukin-12 may kill tumor cells by stopping blood flow to the tumor and by stimulating a person's white blood cells to kill cancer cells. Interleukin-2 may stimulate a person's white blood cells to kill cancer cells. Combining the two drugs may kill more cancer cells

Interventions

  • OTHER laboratory biomarker analysis
  • BIOLOGICAL aldesleukin
  • BIOLOGICAL recombinant interleukin-12

Trial Details

FieldValue
Enrollment Target 25 participants
Start Date 2000-03
Phase Phase 1
National Cancer Institute (NCI)

3,257 total trials

What the finished NCT00005604 record still lists

NCT00005604 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 25 participants, a relatively small participant target, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (58% lower).

The record links to 0 conditions, and to 3 interventions - of which laboratory biomarker analysis is the first listed.

NCT00005604 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT00005604 about?

NCT00005604 is a clinical study titled "Interleukin-12 Plus Interleukin-2 in Treating Patients With Advanced Solid Tumors". Phase I trial to study the effectiveness of interleukin-12 plus interleukin-2 in treating patients who have advanced solid tumors. Interleukin-12 may kill tumor cells by stopping blood flow to the tumor and by stimulating a person's white blood cells to kill cancer cells. Interleukin-2 may stimulate...

What is the current status of trial NCT00005604?

This trial is currently completed. It is a Phase 1 study. The enrollment target is 25 participants. The study started on 2000-03.

What interventions are being tested in trial NCT00005604?

The interventions under investigation include: laboratory biomarker analysis (OTHER), aldesleukin (BIOLOGICAL), recombinant interleukin-12 (BIOLOGICAL).

Who is sponsoring clinical trial NCT00005604?

This trial is sponsored by National Cancer Institute (NCI), which has 3,257 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT00005604's enrollment target sits among peer trials

25 1495th of 2000 higher than 481 of 2,000 other Phase 1 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT00005604, the US trial registry maintained by the National Library of Medicine. NCT00005604 (small enrollment · none site footprint · completed) retrieved and formatted by PlainTrial, see methodology.