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NCT00004495 · ClinicalTrials.gov registry record · NA
Randomized Study of Folic Acid Therapy for Hyperhomocysteinemia in Patients With End Stage Renal Disease Receiving Hemodialysis
A NA study, sponsored by Georgetown University.
- Completed
- Registry status
- NA
- Development phase
- 84
- Enrollment target
NCT00004495: Completed NA study, sponsored by Georgetown University.
NCT00004495 is a NA study that has completed, run by Georgetown University. The registered enrollment target is 84 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (94% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT00004495, a NA study, has completed, sponsored by Georgetown University.
- COMPLETED
- Registry status
- NA
- Development phase
- 84 participants
- Enrollment target
Study Summary
OBJECTIVES: I. Compare the efficacy of two doses of folic acid in normalizing plasma total homocysteine concentration in patients with end stage renal disease receiving regular hemodialysis therapy resulting in hyperhomocysteinemia. II. Determine the requirement of co-supplementation with extra pyridoxine (vitamin B6) and cyanocobalamin (vitamin B12) daily in these patients. III. Assess the safety and tolerability of this therapy in these patients.
Interventions
- DRUG pyridoxine
- DRUG cyanocobalamin
- DRUG folic acid
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 84 participants |
| Start Date | 1999-06 |
| Est. Completion | 2000-09 |
| Phase | NA |
What the finished NCT00004495 record still lists
NCT00004495 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 84 participants, a relatively small participant target, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (94% lower).
The record links to 0 conditions, and to 3 interventions - of which pyridoxine is the first listed.
NCT00004495 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT00004495 about?
NCT00004495 is a clinical study titled "Randomized Study of Folic Acid Therapy for Hyperhomocysteinemia in Patients With End Stage Renal Disease Receiving Hemodialysis". OBJECTIVES: I. Compare the efficacy of two doses of folic acid in normalizing plasma total homocysteine concentration in patients with end stage renal disease receiving regular hemodialysis therapy resulting in hyperhomocysteinemia. II. Determine the requirement of co-supplementation with extra pyr...
What is the current status of trial NCT00004495?
This trial is currently completed. It is a NA study. The enrollment target is 84 participants. The study started on 1999-06. Estimated completion is 2000-09.
What interventions are being tested in trial NCT00004495?
The interventions under investigation include: pyridoxine (DRUG), cyanocobalamin (DRUG), folic acid (DRUG).
Who is sponsoring clinical trial NCT00004495?
This trial is sponsored by Georgetown University, which has 227 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT00004495's enrollment target sits among peer trials
84 983rd of 2000 higher than 1,011 of 2,000 other NA trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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