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NCT00004363 · ClinicalTrials.gov registry record
Study of the Pathogenesis and Pathophysiology of Familial Neurohypophyseal Diabetes Insipidus
A clinical trial of Diabetes Insipidus and Diabetes Insipidus, Neurohypophyseal, sponsored by National Center for Research Resources (NCRR).
- Completed
- Registry status
- 1
- Study location
NCT00004363 is a study of Diabetes Insipidus and Diabetes Insipidus, Neurohypophyseal that has completed, run by National Center for Research Resources (NCRR). The trial reports 1 study location across 1 state.
The verdict
NCT00004363, a study of Diabetes Insipidus and Diabetes Insipidus, Neurohypophyseal, has completed, sponsored by National Center for Research Resources (NCRR).
- COMPLETED
- Registry status
- 1
- Study location
Study Summary
OBJECTIVES: I. Determine whether diverse mutations of the vasopressin-neurophysin II (AVP-NPII) gene cause autosomal dominant familial neurohypophyseal diabetes insipidus by directing the production of an abnormal preprohormone. II. Determine whether the AVP-NPII gene-directed preprohormone accumulates and destroys magnocellular neurons because it cannot be folded and processed efficiently.
Conditions Studied
Interventions
- DRUG chlorpropamide
- DRUG desmopressin
Study Locations (1)
Illinois
- Northwestern University Medical School - Chicago
Trial Details
| Field | Value |
|---|---|
| Start Date | 1995-12 |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT00004363
The ClinicalTrials.gov registry entry for NCT00004363 describes a study currently listed as completed, categorized as an unspecified phase. An enrollment target was not published in the registry record, which is common for early-stage or observational entries. The listed sponsor is National Center for Research Resources (NCRR), which has 94 total studies on file at ClinicalTrials.gov.
The record links to 2 conditions, with Diabetes Insipidus appearing as the primary indexed condition, and to 2 interventions - of which chlorpropamide is the first listed.
NCT00004363 reports 1 study location spanning 1 distinct geographic area - top geographies include Illinois.
Frequently Asked Questions
What is clinical trial NCT00004363 about?
NCT00004363 is a clinical study titled "Study of the Pathogenesis and Pathophysiology of Familial Neurohypophyseal Diabetes Insipidus". OBJECTIVES: I. Determine whether diverse mutations of the vasopressin-neurophysin II (AVP-NPII) gene cause autosomal dominant familial neurohypophyseal diabetes insipidus by directing the production of an abnormal preprohormone. II. Determine whether the AVP-NPII gene-directed preprohormone accumul...
What is the current status of trial NCT00004363?
This trial is currently completed. The study started on 1995-12.
What conditions does trial NCT00004363 study?
This clinical trial studies the following conditions: Diabetes Insipidus, Diabetes Insipidus, Neurohypophyseal.
What interventions are being tested in trial NCT00004363?
The interventions under investigation include: chlorpropamide (DRUG), desmopressin (DRUG).
Who is sponsoring clinical trial NCT00004363?
This trial is sponsored by National Center for Research Resources (NCRR), which has 94 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT00004363 being conducted?
This trial has 1 study location across Illinois. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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