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NCT00004142 · ClinicalTrials.gov registry record · Phase 2
Radiofrequency Ablation Followed By Hepatic Artery Chemotherapy in Treating Patients With Colorectal Cancer That Has Spread to the Liver
A Phase 2 study, sponsored by M.D. Anderson Cancer Center.
- Completed
- Registry status
- Phase 2
- Development phase
- 40
- Enrollment target
NCT00004142: Completed Phase 2 study, sponsored by M.D. Anderson Cancer Center.
NCT00004142 is a Phase 2 study that has completed, run by M.D. Anderson Cancer Center. The registered enrollment target is 40 participants, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (70% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT00004142, a Phase 2 study, has completed, sponsored by M.D. Anderson Cancer Center.
- COMPLETED
- Registry status
- Phase 2
- Development phase
- 40 participants
- Enrollment target
Study Summary
RATIONALE: Radiofrequency ablation may be able to shrink or destroy cancer cells. Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. Chemotherapy delivered directly into the blood vessels of the liver may prevent new tumors from growing. Combining these therapies may be an effective treatment for colorectal cancer that has spread to the liver. PURPOSE: Phase II trial to study the effectiveness of radiofrequency ablation followed by chemotherapy delivered directly into the blood vessels of the liver in treating patients who have colorectal cancer that has spread to the liver.
Interventions
- DRUG Fluorouracil (5-FU)
- DRUG Floxuridine
- PROCEDURE Radiofrequency ablation
- PROCEDURE Conventional surgery
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 40 participants |
| Start Date | 1998-08-05 |
| Est. Completion | 2003-12-09 |
| Phase | Phase 2 |
What the finished NCT00004142 record still lists
NCT00004142 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 40 participants, a relatively small participant target, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (70% lower).
The record links to 0 conditions, and to 4 interventions - of which Fluorouracil (5-FU) is the first listed.
NCT00004142 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT00004142 about?
NCT00004142 is a clinical study titled "Radiofrequency Ablation Followed By Hepatic Artery Chemotherapy in Treating Patients With Colorectal Cancer That Has Spread to the Liver". RATIONALE: Radiofrequency ablation may be able to shrink or destroy cancer cells. Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. Chemotherapy delivered directly into the blood vessels of the liver may prevent new tumors from growing. Comb...
What is the current status of trial NCT00004142?
This trial is currently completed. It is a Phase 2 study. The enrollment target is 40 participants. The study started on 1998-08-05. Estimated completion is 2003-12-09.
What interventions are being tested in trial NCT00004142?
The interventions under investigation include: Fluorouracil (5-FU) (DRUG), Floxuridine (DRUG), Radiofrequency ablation (PROCEDURE), Conventional surgery (PROCEDURE).
Who is sponsoring clinical trial NCT00004142?
This trial is sponsored by M.D. Anderson Cancer Center, which has 2,692 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT00004142's enrollment target sits among peer trials
40 1362nd of 2000 higher than 542 of 2,000 other Phase 2 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 2 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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