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NCT00003917 · ClinicalTrials.gov registry record · Phase 3

Topotecan in Treating Patients With Relapsed Small Cell Lung Cancer

A Phase 3 study, sponsored by Case Comprehensive Cancer Center.

Completed
Registry status
Phase 3
Development phase
4
Enrollment target

NCT00003917: Completed Phase 3 study, sponsored by Case Comprehensive Cancer Center.

NCT00003917 is a Phase 3 study that has completed, run by Case Comprehensive Cancer Center. The registered enrollment target is 4 participants, below the 772-participant average among 15,282 other Phase 3 trials with a reported enrollment target (99% lower). According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT00003917, a Phase 3 study, has completed, sponsored by Case Comprehensive Cancer Center.

COMPLETED
Registry status
Phase 3
Development phase
4 participants
Enrollment target

Study Summary

RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. It is not yet known if topotecan is more effective given by infusion or by mouth. PURPOSE: Randomized phase III trial to compare the effectiveness of topotecan given by infusion with that of topotecan given by mouth in treating patients who have small cell lung cancer that has relapsed following previous therapy.

Interventions

  • DRUG topotecan hydrochloride

Trial Details

FieldValue
Enrollment Target 4 participants
Start Date 1999-03
Est. Completion 2001-11
Phase Phase 3
Case Comprehensive Cancer Center

407 total trials

What the finished NCT00003917 record still lists

NCT00003917 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 4 participants, a relatively small participant target, below the 772-participant average among 15,282 other Phase 3 trials with a reported enrollment target (99% lower).

The record links to 0 conditions, and to 1 intervention - of which topotecan hydrochloride is the first listed.

NCT00003917 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT00003917 about?

NCT00003917 is a clinical study titled "Topotecan in Treating Patients With Relapsed Small Cell Lung Cancer". RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. It is not yet known if topotecan is more effective given by infusion or by mouth. PURPOSE: Randomized phase III trial to compare the effectiveness of topotecan given by infusion w...

What is the current status of trial NCT00003917?

This trial is currently completed. It is a Phase 3 study. The enrollment target is 4 participants. The study started on 1999-03. Estimated completion is 2001-11.

What interventions are being tested in trial NCT00003917?

The interventions under investigation include: topotecan hydrochloride (DRUG).

Who is sponsoring clinical trial NCT00003917?

This trial is sponsored by Case Comprehensive Cancer Center, which has 407 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT00003917's enrollment target sits among peer trials

4 1998th of 2000 higher than 2 of 2,000 other Phase 3 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Phase 3 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT00003917, the US trial registry maintained by the National Library of Medicine. NCT00003917 (small enrollment · none site footprint · completed) retrieved and formatted by PlainTrial, see methodology.