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NCT00003563 · ClinicalTrials.gov registry record · Phase 3
Radiation Therapy Plus Gadolinium Texaphyrin in Treating Patients With Brain Metastases
A Phase 3 study, sponsored by Pharmacyclics.
- Completed
- Registry status
- Phase 3
- Development phase
- 430
- Enrollment target
NCT00003563: Completed Phase 3 study, sponsored by Pharmacyclics.
NCT00003563 is a Phase 3 study that has completed, run by Pharmacyclics. The registered enrollment target is 430 participants, below the 772-participant average among 15,282 other Phase 3 trials with a reported enrollment target (44% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT00003563, a Phase 3 study, has completed, sponsored by Pharmacyclics.
- COMPLETED
- Registry status
- Phase 3
- Development phase
- 430 participants
- Enrollment target
Study Summary
RATIONALE: Radiation therapy uses high-energy x-rays to damage tumor cells. Gadolinium texaphyrin may increase the effectiveness of radiation therapy by making tumor cells more sensitive to radiation. It is not yet known whether giving gadolinium texaphyrin with radiation therapy is more effective than radiation therapy alone in treating brain metastases. PURPOSE: Randomized phase III trial to compare the effectiveness of radiation therapy with or without gadolinium texaphyrin in treating patients who have brain metastases.
Interventions
- RADIATION WBRT
- DRUG MGd
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 430 participants |
| Start Date | 1998-08 |
| Est. Completion | 2005-06 |
| Phase | Phase 3 |
What the finished NCT00003563 record still lists
NCT00003563 is an interventional study that assigns participants to a tested intervention. The registered 430 participants enrollment target is mid-sized for trials with a published cap, below the 772-participant average among 15,282 other Phase 3 trials with a reported enrollment target (44% lower).
The record links to 0 conditions, and to 2 interventions - of which WBRT is the first listed.
NCT00003563 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT00003563 about?
NCT00003563 is a clinical study titled "Radiation Therapy Plus Gadolinium Texaphyrin in Treating Patients With Brain Metastases". RATIONALE: Radiation therapy uses high-energy x-rays to damage tumor cells. Gadolinium texaphyrin may increase the effectiveness of radiation therapy by making tumor cells more sensitive to radiation. It is not yet known whether giving gadolinium texaphyrin with radiation therapy is more effective t...
What is the current status of trial NCT00003563?
This trial is currently completed. It is a Phase 3 study. The enrollment target is 430 participants. The study started on 1998-08. Estimated completion is 2005-06.
What interventions are being tested in trial NCT00003563?
The interventions under investigation include: WBRT (RADIATION), MGd (DRUG).
Who is sponsoring clinical trial NCT00003563?
This trial is sponsored by Pharmacyclics, which has 54 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT00003563's enrollment target sits among peer trials
430 877th of 2000 higher than 1,123 of 2,000 other Phase 3 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 3 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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