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NCT00003478 · ClinicalTrials.gov registry record · Phase 1
Radiolabeled Monoclonal Antibody Therapy in Treating Patients With Primary Brain Tumors
A Phase 1 study, sponsored by Duke University.
- Completed
- Registry status
- Phase 1
- Development phase
- 10
- Enrollment target
NCT00003478: Completed Phase 1 study, sponsored by Duke University.
NCT00003478 is a Phase 1 study that has completed, run by Duke University. The registered enrollment target is 10 participants, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (83% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT00003478, a Phase 1 study, has completed, sponsored by Duke University.
- COMPLETED
- Registry status
- Phase 1
- Development phase
- 10 participants
- Enrollment target
Study Summary
RATIONALE: Monoclonal antibodies can locate tumor cells and deliver radioactive tumor-killing substances such as radioactive iodine to them without harming normal cells. PURPOSE: This randomized phase I/II trial is studying the side effects, best way to give, and best dose of radiolabeled monoclonal antibody and to see how well it works in treating patients with primary brain tumors.
Interventions
- PROCEDURE conventional surgery
- RADIATION radiation therapy
- RADIATION iodine I 131 monoclonal antibody 81C6
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 10 participants |
| Start Date | 1997-10 |
| Est. Completion | 2007-07 |
| Phase | Phase 1 |
What the finished NCT00003478 record still lists
NCT00003478 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 10 participants, a relatively small participant target, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (83% lower).
The record links to 0 conditions, and to 3 interventions - of which conventional surgery is the first listed.
NCT00003478 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT00003478 about?
NCT00003478 is a clinical study titled "Radiolabeled Monoclonal Antibody Therapy in Treating Patients With Primary Brain Tumors". RATIONALE: Monoclonal antibodies can locate tumor cells and deliver radioactive tumor-killing substances such as radioactive iodine to them without harming normal cells. PURPOSE: This randomized phase I/II trial is studying the side effects, best way to give, and best dose of radiolabeled monoclona...
What is the current status of trial NCT00003478?
This trial is currently completed. It is a Phase 1 study. The enrollment target is 10 participants. The study started on 1997-10. Estimated completion is 2007-07.
What interventions are being tested in trial NCT00003478?
The interventions under investigation include: conventional surgery (PROCEDURE), radiation therapy (RADIATION), iodine I 131 monoclonal antibody 81C6 (RADIATION).
Who is sponsoring clinical trial NCT00003478?
This trial is sponsored by Duke University, which has 1,725 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT00003478's enrollment target sits among peer trials
10 1913th of 2000 higher than 46 of 2,000 other Phase 1 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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