Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.

NCT00003466 · ClinicalTrials.gov registry record · Phase 2

Temozolomide in Treating Patients With Progressive Low-Grade Glioma

A Phase 2 study, sponsored by Duke University.

Completed
Registry status
Phase 2
Development phase
100
Enrollment target

NCT00003466: Completed Phase 2 study, sponsored by Duke University.

NCT00003466 is a Phase 2 study that has completed, run by Duke University. The registered enrollment target is 100 participants, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (25% lower). According to ClinicalTrials.gov, the official US trial registry.

View on ClinicalTrials.gov ↗

View your shortlist →

The verdict

NCT00003466, a Phase 2 study, has completed, sponsored by Duke University.

COMPLETED
Registry status
Phase 2
Development phase
100 participants
Enrollment target

Study Summary

RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. PURPOSE: This phase II trial is studying how well temozolomide works in treating patients with progressive low-grade glioma.

Interventions

  • DRUG temozolomide

Trial Details

FieldValue
Enrollment Target 100 participants
Start Date 1998-03
Est. Completion 2005-07
Phase Phase 2
Duke University

1,725 total trials

What the finished NCT00003466 record still lists

NCT00003466 is an interventional study that assigns participants to a tested intervention. The registered 100 participants enrollment target is mid-sized for trials with a published cap, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (25% lower).

The record links to 0 conditions, and to 1 intervention - of which temozolomide is the first listed.

NCT00003466 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT00003466 about?

NCT00003466 is a clinical study titled "Temozolomide in Treating Patients With Progressive Low-Grade Glioma". RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. PURPOSE: This phase II trial is studying how well temozolomide works in treating patients with progressive low-grade glioma.

What is the current status of trial NCT00003466?

This trial is currently completed. It is a Phase 2 study. The enrollment target is 100 participants. The study started on 1998-03. Estimated completion is 2005-07.

What interventions are being tested in trial NCT00003466?

The interventions under investigation include: temozolomide (DRUG).

Who is sponsoring clinical trial NCT00003466?

This trial is sponsored by Duke University, which has 1,725 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT00003466's enrollment target sits among peer trials

100 672nd of 2000 higher than 1,263 of 2,000 other Phase 2 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Phase 2 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

Nationwide trials with similar profiles

Cross-condition peers matched on enrollment target and registry start date, not the same-condition list above.

Similar enrollment target

  • NCT01048281 · 100 participants

    Clinical & Pathological Studies of Upper Gastrointestinal Carcinoma

  • NCT01161199 · 100 participants

    The Use of Leukapheresis to Support HIV Pathogenesis Studies

  • NCT01327690 · 100 participants · Early Phase 1

    Mental Health in Veterans and Families After Group Therapies

  • NCT01730781 · 100 participants

    Imaging Cannabinoid Receptors Using Positron Emission Tomography (PET) Scanning

Similar registry start date

  • NCT05988463 · started 2027-01-01 · Phase 1

    Dose-Escalation Study of Artesunate Patients With IPF

  • NCT07219706 · started 2026-12-10 · NA

    Dietary Fiber and Time Restricted Eating

  • NCT02831335 · started 2026-12-01

    Technical Development of Multi-Parametric Renocerebral MRI

  • NCT05962346 · started 2026-12 · NA

    Fetal Endoscopic Tracheal Occlusion for Congenital Diaphragmatic Hernia

Source: ClinicalTrials.gov NCT00003466, the US trial registry maintained by the National Library of Medicine. NCT00003466 (mid enrollment · none site footprint · completed) retrieved and formatted by PlainTrial, see methodology.