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NCT00003397 · ClinicalTrials.gov registry record · Phase 2

Peripheral Stem Cell Transplantation Plus Combination Chemotherapy and Monoclonal Antibody Therapy in Treating Patients With Non-Hodgkin's Lymphoma

A Phase 2 study, sponsored by University of Maryland, Baltimore.

Completed
Registry status
Phase 2
Development phase
25
Enrollment target

NCT00003397: Completed Phase 2 study, sponsored by University of Maryland, Baltimore.

NCT00003397 is a Phase 2 study that has completed, run by University of Maryland, Baltimore. The registered enrollment target is 25 participants, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (81% lower). According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT00003397, a Phase 2 study, has completed, sponsored by University of Maryland, Baltimore.

COMPLETED
Registry status
Phase 2
Development phase
25 participants
Enrollment target

Study Summary

RATIONALE: Drugs used in chemotherapy use different ways to stop cancer cells from dividing so they stop growing or die. Combining chemotherapy with peripheral stem cell transplantation may allow the doctor to give higher doses of chemotherapy drugs and kill more cancer cells. Monoclonal antibodies can locate cancer cells and either kill them or deliver cancer-killing substances to them without harming normal cells. PURPOSE: Phase II trial to study the effectiveness of peripheral stem cell transplantation plus combination chemotherapy and rituximab in treating patients with non-Hodgkin's lymphoma.

Interventions

  • DRUG cisplatin
  • BIOLOGICAL rituximab
  • DRUG carmustine
  • BIOLOGICAL filgrastim
  • BIOLOGICAL sargramostim

Trial Details

FieldValue
Enrollment Target 25 participants
Start Date 1998-09
Est. Completion 2002-12
Phase Phase 2
University of Maryland, Baltimore

560 total trials

What the finished NCT00003397 record still lists

NCT00003397 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 25 participants, a relatively small participant target, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (81% lower).

The record links to 0 conditions, and to 5 interventions - of which cisplatin is the first listed.

NCT00003397 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT00003397 about?

NCT00003397 is a clinical study titled "Peripheral Stem Cell Transplantation Plus Combination Chemotherapy and Monoclonal Antibody Therapy in Treating Patients With Non-Hodgkin's Lymphoma". RATIONALE: Drugs used in chemotherapy use different ways to stop cancer cells from dividing so they stop growing or die. Combining chemotherapy with peripheral stem cell transplantation may allow the doctor to give higher doses of chemotherapy drugs and kill more cancer cells. Monoclonal antibodies ...

What is the current status of trial NCT00003397?

This trial is currently completed. It is a Phase 2 study. The enrollment target is 25 participants. The study started on 1998-09. Estimated completion is 2002-12.

What interventions are being tested in trial NCT00003397?

The interventions under investigation include: cisplatin (DRUG), rituximab (BIOLOGICAL), carmustine (DRUG), filgrastim (BIOLOGICAL), sargramostim (BIOLOGICAL).

Who is sponsoring clinical trial NCT00003397?

This trial is sponsored by University of Maryland, Baltimore, which has 560 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT00003397's enrollment target sits among peer trials

25 1719th of 2000 higher than 245 of 2,000 other Phase 2 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Phase 2 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT00003397, the US trial registry maintained by the National Library of Medicine. NCT00003397 (small enrollment · none site footprint · completed) retrieved and formatted by PlainTrial, see methodology.