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NCT00003335 · ClinicalTrials.gov registry record · Phase 2
Umbilical Cord Blood Transplantation in Treating Patients With High-Risk Hematologic Cancer
A Phase 2 study, sponsored by Case Comprehensive Cancer Center.
- Completed
- Registry status
- Phase 2
- Development phase
- 44
- Enrollment target
NCT00003335: Completed Phase 2 study, sponsored by Case Comprehensive Cancer Center.
NCT00003335 is a Phase 2 study that has completed, run by Case Comprehensive Cancer Center. The registered enrollment target is 44 participants, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (67% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT00003335, a Phase 2 study, has completed, sponsored by Case Comprehensive Cancer Center.
- COMPLETED
- Registry status
- Phase 2
- Development phase
- 44 participants
- Enrollment target
Study Summary
RATIONALE: Umbilical cord blood transplantation may allow doctors to give higher doses of chemotherapy or radiation therapy and kill more cancer cells. PURPOSE: This phase II trial is studying allogeneic umbilical cord blood transplantation to see how well it works when given with chemotherapy or radiation therapy in treating patients with high-risk hematologic cancer.
Primary Outcome
The primary study end point will be hematologic engraftment. Engraftment is defined as achieving ANC larger than or equal to 500 ul/mm3 of donor origin for three consecutive measurements on different days by day +42.
Interventions
- DRUG methylprednisolone
- DRUG melphalan
- DRUG busulfan
- DRUG cyclosporine
- BIOLOGICAL anti-thymocyte globulin
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 44 participants |
| Start Date | 1998-01 |
| Est. Completion | 2012-01 |
| Phase | Phase 2 |
What the finished NCT00003335 record still lists
NCT00003335 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 44 participants, a relatively small participant target, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (67% lower).
The record links to 0 conditions, and to 5 interventions - of which methylprednisolone is the first listed.
NCT00003335 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT00003335 about?
NCT00003335 is a clinical study titled "Umbilical Cord Blood Transplantation in Treating Patients With High-Risk Hematologic Cancer". RATIONALE: Umbilical cord blood transplantation may allow doctors to give higher doses of chemotherapy or radiation therapy and kill more cancer cells. PURPOSE: This phase II trial is studying allogeneic umbilical cord blood transplantation to see how well it works when given with chemotherapy or r...
What is the current status of trial NCT00003335?
This trial is currently completed. It is a Phase 2 study. The enrollment target is 44 participants. The study started on 1998-01. Estimated completion is 2012-01.
What interventions are being tested in trial NCT00003335?
The interventions under investigation include: methylprednisolone (DRUG), melphalan (DRUG), busulfan (DRUG), cyclosporine (DRUG), anti-thymocyte globulin (BIOLOGICAL).
Who is sponsoring clinical trial NCT00003335?
This trial is sponsored by Case Comprehensive Cancer Center, which has 407 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT00003335's enrollment target sits among peer trials
44 1322nd of 2000 higher than 669 of 2,000 other Phase 2 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 2 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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