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NCT00002778 · ClinicalTrials.gov registry record · Phase 2

Sargramostim Following Allogeneic Bone Marrow Transplantation in Treating Patients With Chronic Myelogenous Leukemia

A Phase 2 study, sponsored by Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins.

Terminated
Registry status
Phase 2
Development phase
40
Enrollment target

NCT00002778 is a Phase 2 study that was terminated before completion, run by Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins. The registered enrollment target is 40 participants.

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The verdict

NCT00002778, a Phase 2 study, was terminated before completion, sponsored by Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins.

TERMINATED
Registry status
Phase 2
Development phase
40 participants
Enrollment target

Study Summary

RATIONALE: Drugs used in chemotherapy work in different ways to stop cancer cells from dividing so they stop growing or die. Combining chemotherapy with allogeneic bone marrow transplantation may allow the doctor to give higher doses of chemotherapy drugs and kill more cancer cells. Colony-stimulating factors such as sargramostim may increase the number of immune cells found in bone marrow or peripheral blood, and may help a person's immune system recover from the side effects of chemotherapy. PURPOSE: Phase II trial to study the effectiveness of allogeneic bone marrow transplantation followed by sargramostim in treating patients who have chronic myelogenous leukemia.

Interventions

  • PROCEDURE allogeneic bone marrow transplantation
  • BIOLOGICAL sargramostim
  • BIOLOGICAL therapeutic allogeneic lymphocytes
  • PROCEDURE in vitro-treated bone marrow transplantation

Trial Details

FieldValue
Enrollment Target 40 participants
Start Date 1995-02
Est. Completion 2010-07
Phase Phase 2

What the Registry Record Tells You About NCT00002778

The ClinicalTrials.gov registry entry for NCT00002778 describes a study currently listed as terminated, categorized as Phase 2. The registered enrollment target is 40 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins, which has 523 total studies on file at ClinicalTrials.gov.

The record links to 0 conditions, and to 4 interventions - of which allogeneic bone marrow transplantation is the first listed.

NCT00002778 reports 0 study locations.

Frequently Asked Questions

What is clinical trial NCT00002778 about?

NCT00002778 is a clinical study titled "Sargramostim Following Allogeneic Bone Marrow Transplantation in Treating Patients With Chronic Myelogenous Leukemia". RATIONALE: Drugs used in chemotherapy work in different ways to stop cancer cells from dividing so they stop growing or die. Combining chemotherapy with allogeneic bone marrow transplantation may allow the doctor to give higher doses of chemotherapy drugs and kill more cancer cells. Colony-stimulati...

What is the current status of trial NCT00002778?

This trial is currently terminated. It is a Phase 2 study. The enrollment target is 40 participants. The study started on 1995-02. Estimated completion is 2010-07.

What interventions are being tested in trial NCT00002778?

The interventions under investigation include: allogeneic bone marrow transplantation (PROCEDURE), sargramostim (BIOLOGICAL), therapeutic allogeneic lymphocytes (BIOLOGICAL), in vitro-treated bone marrow transplantation (PROCEDURE).

Who is sponsoring clinical trial NCT00002778?

This trial is sponsored by Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins, which has 523 total clinical trials registered on ClinicalTrials.gov.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

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