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NCT00002708 · ClinicalTrials.gov registry record · Phase 3

Radiation Therapy With or Without Radiosurgery in Treating Patients With Brain Metastases

A Phase 3 study, sponsored by Radiation Therapy Oncology Group.

Completed
Registry status
Phase 3
Development phase
333
Enrollment target

NCT00002708: Completed Phase 3 study, sponsored by Radiation Therapy Oncology Group.

NCT00002708 is a Phase 3 study that has completed, run by Radiation Therapy Oncology Group. The registered enrollment target is 333 participants, below the 772-participant average among 15,282 other Phase 3 trials with a reported enrollment target (57% lower). According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT00002708, a Phase 3 study, has completed, sponsored by Radiation Therapy Oncology Group.

COMPLETED
Registry status
Phase 3
Development phase
333 participants
Enrollment target

Study Summary

RATIONALE: Radiation therapy uses high-energy x-rays to damage tumor cells. It is not yet known whether giving radiation therapy during surgery is more effective than standard radiation therapy in treating brain metastases. PURPOSE: Randomized phase III trial to compare the effectiveness of radiation therapy with or without radiosurgery in treating patients with brain metastases that cannot be removed during surgery.

Interventions

  • RADIATION radiation therapy
  • RADIATION stereotactic radiosurgery
  • PROCEDURE surgical procedure

Trial Details

FieldValue
Enrollment Target 333 participants
Start Date 1996-01
Est. Completion 2004-12
Phase Phase 3
Radiation Therapy Oncology Group

144 total trials

What the finished NCT00002708 record still lists

NCT00002708 is an interventional study that assigns participants to a tested intervention. The registered 333 participants enrollment target is mid-sized for trials with a published cap, below the 772-participant average among 15,282 other Phase 3 trials with a reported enrollment target (57% lower).

The record links to 0 conditions, and to 3 interventions - of which radiation therapy is the first listed.

NCT00002708 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT00002708 about?

NCT00002708 is a clinical study titled "Radiation Therapy With or Without Radiosurgery in Treating Patients With Brain Metastases". RATIONALE: Radiation therapy uses high-energy x-rays to damage tumor cells. It is not yet known whether giving radiation therapy during surgery is more effective than standard radiation therapy in treating brain metastases. PURPOSE: Randomized phase III trial to compare the effectiveness of radiati...

What is the current status of trial NCT00002708?

This trial is currently completed. It is a Phase 3 study. The enrollment target is 333 participants. The study started on 1996-01. Estimated completion is 2004-12.

What interventions are being tested in trial NCT00002708?

The interventions under investigation include: radiation therapy (RADIATION), stereotactic radiosurgery (RADIATION), surgical procedure (PROCEDURE).

Who is sponsoring clinical trial NCT00002708?

This trial is sponsored by Radiation Therapy Oncology Group, which has 144 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT00002708's enrollment target sits among peer trials

333 1061st of 2000 higher than 940 of 2,000 other Phase 3 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Phase 3 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT00002708, the US trial registry maintained by the National Library of Medicine. NCT00002708 (mid enrollment · none site footprint · completed) retrieved and formatted by PlainTrial, see methodology.