Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.

COMPLETED Phase 3

Surgery With or Without Chemotherapy in Treating Patients With Stage IB Cervical Cancer

NCT00002536 · View on ClinicalTrials.gov ↗

Study Summary

RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. Giving chemotherapy drugs before surgery may shrink the tumor so that it can be removed during surgery. PURPOSE: Randomized phase III trial to compare surgery with or without chemotherapy in treating patients who have stage IB cervical cancer.

Conditions Studied

Interventions

  • DRUG cisplatin
  • RADIATION radiation therapy
  • DRUG vincristine sulfate
  • PROCEDURE surgical procedure

Study Locations (20)

California

  • Southern California Permanante Medical Group — Bellflower
  • Jonsson Comprehensive Cancer Center, UCLA — Los Angeles
  • Community Hospital of Los Gatos — Los Gatos
  • Chao Family Comprehensive Cancer Center — Orange

Illinois

  • Rush-Presbyterian-St. Luke's Medical Center — Chicago
  • University of Chicago Cancer Research Center — Chicago

Massachusetts

  • Tufts University School of Medicine — Boston
  • University of Massachusetts Memorial Medical Center — Worcester

Alabama

  • University of Alabama at Birmingham Comprehensive Cancer Center — Birmingham

Colorado

  • University of Colorado Cancer Center — Denver

District of Columbia

  • Walter Reed Army Medical Center — Washington D.C.

Florida

  • H. Lee Moffitt Cancer Center and Research Institute — Tampa

Indiana

  • Indiana University Cancer Center — Indianapolis

Trial Details

FieldValue
Start Date 1996-12
Phase Phase 3

Sponsor

Gynecologic Oncology Group

61 total trials

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Full Details on ClinicalTrials.gov ↗

What the Registry Record Tells You About NCT00002536

The ClinicalTrials.gov registry entry for NCT00002536 describes a study currently listed as completed. It is categorized as Phase 3, which is the standard way researchers label where a study sits along the investigational pathway from early safety work through later efficacy and post-marketing evaluation. An enrollment target was not published in the registry record, which is common for early-stage or observational entries. The listed sponsor is Gynecologic Oncology Group, which has 61 total studies on file at ClinicalTrials.gov, and sponsors are the parties responsible for study design, oversight, and regulatory filings.

The record links to 1 condition, with Cervical Cancer appearing as the primary indexed condition, and to 4 interventions — of which cisplatin is the first listed. Interventions can include drugs, devices, procedures, behavioral programs, or observational arms, and each is tracked as a separate registry field so that downstream queries can filter accurately. When a trial lists multiple interventions, it usually reflects a multi-arm design or a comparison protocol rather than a single treatment being tested in isolation. The brief summary published in the registry is the clearest source of protocol intent and should be read before drawing conclusions from any sidebar tags.

Geographic footprint matters for practical reasons: NCT00002536 reports 20 study locations spanning 15 distinct geographic areas — top geographies include California, Illinois, Massachusetts. A larger site network tends to correlate with broader recruitment capacity, but it does not imply anything about study quality, and site-level enrollment status can diverge from the overall registry status shown above. Every data point on this page comes from the public ClinicalTrials.gov dataset and is reproduced here for reference only; it is not a medical recommendation, an endorsement of the sponsor, or an invitation to enroll. Verify current status, eligibility criteria, and contact details directly at ClinicalTrials.gov, and discuss any participation decision with your own healthcare provider.

Frequently Asked Questions

What is clinical trial NCT00002536 about?

NCT00002536 is a clinical study titled "Surgery With or Without Chemotherapy in Treating Patients With Stage IB Cervical Cancer". RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. Giving chemotherapy drugs before surgery may shrink the tumor so that it can be removed during surgery. PURPOSE: Randomized phase III trial to compare surgery with or without chem...

What is the current status of trial NCT00002536?

This trial is currently completed. It is a Phase 3 study. The study started on 1996-12.

What conditions does trial NCT00002536 study?

This clinical trial studies the following conditions: Cervical Cancer. These conditions were identified from the trial registry and reflect the primary focus areas of the research.

What interventions are being tested in trial NCT00002536?

The interventions under investigation include: cisplatin (DRUG), radiation therapy (RADIATION), vincristine sulfate (DRUG), surgical procedure (PROCEDURE). Each intervention is being evaluated for safety and efficacy as part of this clinical study.

Who is sponsoring clinical trial NCT00002536?

This trial is sponsored by Gynecologic Oncology Group, which has 61 total clinical trials registered on ClinicalTrials.gov. The sponsor is responsible for the study's design, funding, and regulatory compliance.

Where is trial NCT00002536 being conducted?

This trial has 20 study locations across Alabama, California, Colorado, District of Columbia, Florida. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Related

Data sourced from official U.S. government datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial