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NCT00002124 · ClinicalTrials.gov registry record · Phase 3

A Double-Blind, Randomized, Dose Response Study of Three Doses of Delavirdine Mesylate (U-90152S) in Combination With Zidovudine (ZDV) Versus ZDV Alone in HIV-1 Infected Individuals With CD4 Counts of 200-500mm3

A Phase 3 study, sponsored by Pharmacia and Upjohn.

Completed
Registry status
Phase 3
Development phase
1,250
Enrollment target

NCT00002124: Completed Phase 3 study, sponsored by Pharmacia and Upjohn.

NCT00002124 is a Phase 3 study that has completed, run by Pharmacia and Upjohn. The registered enrollment target is 1,250 participants, above the 772-participant average among 15,282 other Phase 3 trials with a reported enrollment target (62% higher). According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT00002124, a Phase 3 study, has completed, sponsored by Pharmacia and Upjohn.

COMPLETED
Registry status
Phase 3
Development phase
1,250 participants
Enrollment target

Study Summary

PART I: To evaluate the safety, tolerance, efficacy, and pharmacokinetics of three fixed doses of delavirdine mesylate (DLV) in combination with zidovudine (AZT) versus AZT alone in HIV-positive patients. PART II: To evaluate the safety, tolerance, efficacy, and pharmacokinetics of ZDV plus 3TC with or without DLV versus ZDV plus DLV in HIV-positive patients.

Interventions

  • DRUG Zidovudine
  • DRUG Lamivudine
  • DRUG Delavirdine mesylate

Trial Details

FieldValue
Enrollment Target 1,250 participants
Phase Phase 3
Pharmacia and Upjohn

11 total trials

What the finished NCT00002124 record still lists

NCT00002124 is an interventional study that assigns participants to a tested intervention. Its 1,250 participants enrollment target places it among the larger protocols in the corpus, above the 772-participant average among 15,282 other Phase 3 trials with a reported enrollment target (62% higher).

The record links to 0 conditions, and to 3 interventions - of which Zidovudine is the first listed.

NCT00002124 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT00002124 about?

NCT00002124 is a clinical study titled "A Double-Blind, Randomized, Dose Response Study of Three Doses of Delavirdine Mesylate (U-90152S) in Combination With Zidovudine (ZDV) Versus ZDV Alone in HIV-1 Infected Individuals With CD4 Counts of 200-500mm3". PART I: To evaluate the safety, tolerance, efficacy, and pharmacokinetics of three fixed doses of delavirdine mesylate (DLV) in combination with zidovudine (AZT) versus AZT alone in HIV-positive patients. PART II: To evaluate the safety, tolerance, efficacy, and pharmacokinetics of ZDV plus 3TC wit...

What is the current status of trial NCT00002124?

This trial is currently completed. It is a Phase 3 study. The enrollment target is 1,250 participants.

What interventions are being tested in trial NCT00002124?

The interventions under investigation include: Zidovudine (DRUG), Lamivudine (DRUG), Delavirdine mesylate (DRUG).

Who is sponsoring clinical trial NCT00002124?

This trial is sponsored by Pharmacia and Upjohn, which has 11 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT00002124's enrollment target sits among peer trials

1,250 207th of 2000 higher than 1,791 of 2,000 other Phase 3 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Phase 3 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT00002124, the US trial registry maintained by the National Library of Medicine. NCT00002124 (large enrollment · none site footprint · completed) retrieved and formatted by PlainTrial, see methodology.