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NCT00001996 · ClinicalTrials.gov registry record · Phase 2
A Phase II Open Randomized Comparison of 566C80 and Pentamidine Isethionate for the Treatment of Pneumocystis Carinii Pneumonia in AIDS Patients Who Are Intolerant of Trimethoprim / Sulfamethoxazole
A Phase 2 study of HIV Infections and Pneumonia, Pneumocystis Carinii, sponsored by Glaxo Wellcome.
- Completed
- Registry status
- Phase 2
- Development phase
- 20
- Study locations
NCT00001996: Completed Phase 2 study of HIV Infections and Pneumonia, Pneumocystis Carinii, sponsored by Glaxo Wellcome.
NCT00001996 is a Phase 2 study of HIV Infections and Pneumonia, Pneumocystis Carinii that has completed, run by Glaxo Wellcome. The trial reports 20 study locations across 9 states. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT00001996, a Phase 2 study of HIV Infections and Pneumonia, Pneumocystis Carinii, has completed, sponsored by Glaxo Wellcome.
- COMPLETED
- Registry status
- Phase 2
- Development phase
- 20
- Study locations
Study Summary
To compare the safety of atovaquone (566C80) with intravenous (IV) pentamidine for the treatment of mild to moderate Pneumocystis carinii pneumonia (PCP) in AIDS patients who are intolerant of therapy with trimethoprim / sulfamethoxazole (TMP / SMX) by comparing the incidence of premature discontinuation of therapy due to toxicity. To compare the efficacy of 566C80 with intravenous (IV) pentamidine for the treatment of mild to moderate PCP in the same population.
Conditions Studied
Interventions
- DRUG Atovaquone
- DRUG Pentamidine isethionate
Study Locations (20)
California
- East Bay AIDS Ctr - Berkeley
- Kaiser Foundation Hosp - Harbor City
- Cedars Sinai Med Ctr - Los Angeles
- UCLA CARE Ctr - Los Angeles
- UCI Med Ctr - Orange
- AIDS Community Research Consortium - Redwood City
- Davies Med Ctr - San Francisco
- Dr Patrick Joseph - San Ramone
New York
- Beth Israel Med Ctr - New York
- Saint Vincent's Hosp and Med Ctr - New York
- Harlem AIDS Treatment Group / Harlem Hosp Ctr - New York
Massachusetts
- Massachusetts Gen Hosp - Boston
- Boston City Hosp - Boston
Texas
- Gathe, Joseph, M.D. - Houston
- Baylor College of Medicine - Houston
Georgia
- Infectious Disease Research Consortium of Georgia - Atlanta
Ohio
- Univ of Cincinnati - Cincinnati
Oregon
- Portland Veterans Adm Med Ctr / Rsch & Education Grp - Portland
Pennsylvania
- Buckley Braffman Stern Med Associates - Philadelphia
Trial Details
| Field | Value |
|---|---|
| Phase | Phase 2 |
What the finished NCT00001996 record still lists
NCT00001996 is an interventional study that assigns participants to a tested intervention. An enrollment target was not published in the registry record, which is common for early-stage or observational entries.
The record links to 2 conditions, with HIV Infections appearing as the primary indexed condition, and to 2 interventions - of which Atovaquone is the first listed.
NCT00001996 names 20 study sites across 9 states, led by California, New York, Massachusetts.
Frequently Asked Questions
What is clinical trial NCT00001996 about?
NCT00001996 is a clinical study titled "A Phase II Open Randomized Comparison of 566C80 and Pentamidine Isethionate for the Treatment of Pneumocystis Carinii Pneumonia in AIDS Patients Who Are Intolerant of Trimethoprim / Sulfamethoxazole". To compare the safety of atovaquone (566C80) with intravenous (IV) pentamidine for the treatment of mild to moderate Pneumocystis carinii pneumonia (PCP) in AIDS patients who are intolerant of therapy with trimethoprim / sulfamethoxazole (TMP / SMX) by comparing the incidence of premature discontinu...
What is the current status of trial NCT00001996?
This trial is currently completed. It is a Phase 2 study.
What conditions does trial NCT00001996 study?
This clinical trial studies the following conditions: HIV Infections, Pneumonia, Pneumocystis Carinii.
What interventions are being tested in trial NCT00001996?
The interventions under investigation include: Atovaquone (DRUG), Pentamidine isethionate (DRUG).
Who is sponsoring clinical trial NCT00001996?
This trial is sponsored by Glaxo Wellcome, which has 65 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT00001996 being conducted?
This trial has 20 study locations across California, Georgia, Massachusetts, New York, Ohio. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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