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NCT00001702 · ClinicalTrials.gov registry record
Evaluation of the Association of Polymorphisms in the Innate Immune System With the Risk for Blastomycosis Dermatitidis Infection in Patients Not Infected With HIV and Complications Associated With Blastomycosis Dermatitidis Infection
A clinical trial, sponsored by National Cancer Institute (NCI).
- Completed
- Registry status
- 400
- Enrollment target
NCT00001702: Completed study, sponsored by National Cancer Institute (NCI).
NCT00001702 is a clinical trial that has completed, run by National Cancer Institute (NCI). The registered enrollment target is 400 participants. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT00001702 has completed, sponsored by National Cancer Institute (NCI).
- COMPLETED
- Registry status
- 400 participants
- Enrollment target
Study Summary
Innate immunity plays an important role for fungal recognition and initiation of fungicidal activity. We hypothesize that subtle differences in different molecules of innate immunity may contribute to either the predisposition or clinical course of infection with Blastomycosis dermatitidis. To test this hypothesis, we propose to analyze the allelic frequencies of 15 different genes (mannose binding lectin, Fc-gamma receptor IIa and IIb, Fc-gamma receptors IIIa and IIIb, myeloperoxidase, tumor necrosis factor-alpha and -beta, interleukin 1A and 1B, interleukin-1 receptor antagonist, interleukin-10, NRAMP-1, chitotriosidase, and chemokine receptor 5) and their intragenic polymorphic forms and to compare this data to the incidence and severity of Blastomycosis dermatitidis infection. With this study we hope to identify a group of molecules of innate immunity which influence the risk and severity of invasive Blastomycosis dermatitidis infection.
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 400 participants |
| Start Date | 1998-07-29 |
What the finished NCT00001702 record still lists
NCT00001702 is an observational study that tracks outcomes without assigning an intervention. The registered 400 participants enrollment target is mid-sized for trials with a published cap.
The record links to 0 conditions, and to 0 interventions.
NCT00001702 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT00001702 about?
NCT00001702 is a clinical study titled "Evaluation of the Association of Polymorphisms in the Innate Immune System With the Risk for Blastomycosis Dermatitidis Infection in Patients Not Infected With HIV and Complications Associated With Blastomycosis Dermatitidis Infection". Innate immunity plays an important role for fungal recognition and initiation of fungicidal activity. We hypothesize that subtle differences in different molecules of innate immunity may contribute to either the predisposition or clinical course of infection with Blastomycosis dermatitidis. To test ...
What is the current status of trial NCT00001702?
This trial is currently completed. The enrollment target is 400 participants. The study started on 1998-07-29.
Who is sponsoring clinical trial NCT00001702?
This trial is sponsored by National Cancer Institute (NCI), which has 3,257 total clinical trials registered on ClinicalTrials.gov.
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