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NCT00001574 · ClinicalTrials.gov registry record
A Pilot Study of 1H-Nuclear Magnetic Resonance Spectroscopic Imaging in Pediatric Patients With Primary and Metastatic Brain Tumors
A clinical trial, sponsored by National Cancer Institute (NCI).
- Completed
- Registry status
- 40
- Enrollment target
NCT00001574: Completed study, sponsored by National Cancer Institute (NCI).
NCT00001574 is a clinical trial that has completed, run by National Cancer Institute (NCI). The registered enrollment target is 40 participants. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT00001574 has completed, sponsored by National Cancer Institute (NCI).
- COMPLETED
- Registry status
- 40 participants
- Enrollment target
Study Summary
Brain tumors represent the most common solid tumor of childhood. Treatment generally entails surgery and radiation, but local recurrence is frequent. Chemotherapy is often used in an adjuvant setting, to delay radiation therapy or for resistant disease. Children with brain tumors are generally followed by imaging studies, such as CT or MRI. Difficulty arises in trying to distinguish tumor regrowth from treatment related edema, necrosis or radiation injury. Proton Nuclear Magnetic Resonance Spectroscopic (NMRS) Imaging is a non-invasive method of detecting and measuring cellular metabolites in vivo. NMRS imaging complements routine MRI by giving chemical information in conjunction with spatial information obtained by MRI. This study will be conducted to determine NMRS imaging patterns before, during and after chemotherapy in pediatric patients with primary or metastatic brain tumors in an attempt to identify and characterize specific patterns of metabolites related to tumor regrowth, tumor response to therapy, edema or necrosis.
Primary Outcome
in vivo measurements of tissue metabolites (NAA, Cho,Cr, Lac) and what they reflect
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 40 participants |
| Start Date | 1997-03-14 |
| Est. Completion | 2019-05-06 |
What the finished NCT00001574 record still lists
NCT00001574 is an observational study that tracks outcomes without assigning an intervention. The registry caps enrollment at 40 participants, a relatively small participant target.
The record links to 0 conditions, and to 0 interventions.
NCT00001574 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT00001574 about?
NCT00001574 is a clinical study titled "A Pilot Study of 1H-Nuclear Magnetic Resonance Spectroscopic Imaging in Pediatric Patients With Primary and Metastatic Brain Tumors". Brain tumors represent the most common solid tumor of childhood. Treatment generally entails surgery and radiation, but local recurrence is frequent. Chemotherapy is often used in an adjuvant setting, to delay radiation therapy or for resistant disease. Children with brain tumors are generally follo...
What is the current status of trial NCT00001574?
This trial is currently completed. The enrollment target is 40 participants. The study started on 1997-03-14. Estimated completion is 2019-05-06.
Who is sponsoring clinical trial NCT00001574?
This trial is sponsored by National Cancer Institute (NCI), which has 3,257 total clinical trials registered on ClinicalTrials.gov.
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