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NCT00001496 · ClinicalTrials.gov registry record
Establishment of Normal Breast Epithelial Cell Lines From Patients at High Risk for Breast Cancer
A clinical trial of Breast Neoplasm and Hereditary Neoplastic Syndrome, sponsored by National Cancer Institute (NCI).
- Completed
- Registry status
- 50
- Enrollment target
- 1
- Study location
NCT00001496: Completed study of Breast Neoplasm and Hereditary Neoplastic Syndrome, sponsored by National Cancer Institute (NCI).
NCT00001496 is a study of Breast Neoplasm and Hereditary Neoplastic Syndrome that has completed, run by National Cancer Institute (NCI). The registered enrollment target is 50 participants, below the 161-participant average among 26 other Breast Neoplasm trials with a reported enrollment target (69% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT00001496, a study of Breast Neoplasm and Hereditary Neoplastic Syndrome, has completed, sponsored by National Cancer Institute (NCI).
- COMPLETED
- Registry status
- 50 participants
- Enrollment target
- 1
- Study location
Study Summary
Women who are at high risk for breast cancer, either because of linkage to high risk breast and ovarian cancer families, or because of a carcinoma in the opposite breast, will be studied. Women will have a physical examination and mammography to ensure that no breast abnormalities are present. Eligible women will undergo biopsy of the breast to obtain normal breast tissue. Short-term cell cultures will be established from this tissue and early passages of the short-term cell lines will be stored. A bank of high risk normal mammary epithelial cells will be established. To further characterize the mammary epithelial cells in this population of women, cell cultures will subsequently be analyzed for their growth and metabolic properties, sensitivity to chemopreventive agents, steroid receptor characteristics, oncogene expression and regulation, and genetic changes.
Conditions Studied
Study Locations (1)
Maryland
- National Cancer Institute (NCI) - Bethesda
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 50 participants |
| Start Date | 1996-01 |
| Est. Completion | 2001-11 |
What the finished NCT00001496 record still lists
NCT00001496 is an observational study that tracks outcomes without assigning an intervention. The registry caps enrollment at 50 participants, a relatively small participant target, below the 161-participant average among 26 other Breast Neoplasm trials with a reported enrollment target (69% lower).
The record links to 2 conditions, with Breast Neoplasm appearing as the primary indexed condition, and to 0 interventions.
NCT00001496 reports a single indexed study location in Maryland.
Frequently Asked Questions
What is clinical trial NCT00001496 about?
NCT00001496 is a clinical study titled "Establishment of Normal Breast Epithelial Cell Lines From Patients at High Risk for Breast Cancer". Women who are at high risk for breast cancer, either because of linkage to high risk breast and ovarian cancer families, or because of a carcinoma in the opposite breast, will be studied. Women will have a physical examination and mammography to ensure that no breast abnormalities are present. Eligi...
What is the current status of trial NCT00001496?
This trial is currently completed. The enrollment target is 50 participants. The study started on 1996-01. Estimated completion is 2001-11.
What conditions does trial NCT00001496 study?
This clinical trial studies the following conditions: Breast Neoplasm, Hereditary Neoplastic Syndrome.
Who is sponsoring clinical trial NCT00001496?
This trial is sponsored by National Cancer Institute (NCI), which has 3,257 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT00001496 being conducted?
This trial has 1 study location across Maryland. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Breast Neoplasm
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT00001496's enrollment target sits among peer trials
50 19th of 26 higher than 8 of 26 other Breast Neoplasm trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Breast Neoplasm trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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