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NCT00001013 · ClinicalTrials.gov registry record · Phase 3

Comparison of Trimetrexate Plus Leucovorin Calcium Rescue Versus Sulfamethoxazole-Trimethoprim in the Treatment of Pneumocystis Carinii Pneumonia (PCP) in Patients With AIDS

A Phase 3 study, sponsored by National Institute of Allergy and Infectious Diseases (NIAID).

Completed
Registry status
Phase 3
Development phase
364
Enrollment target

NCT00001013 is a Phase 3 study that has completed, run by National Institute of Allergy and Infectious Diseases (NIAID). The registered enrollment target is 364 participants.

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The verdict

NCT00001013, a Phase 3 study, has completed, sponsored by National Institute of Allergy and Infectious Diseases (NIAID).

COMPLETED
Registry status
Phase 3
Development phase
364 participants
Enrollment target

Study Summary

To compare the safety and effectiveness of an investigational drug therapy (trimetrexate plus leucovorin calcium) with that of conventional therapy (sulfamethoxazole-trimethoprim) in the treatment of moderately severe Pneumocystis carinii pneumonia (PCP) in patients who have AIDS, are HIV positive, or are at high risk for HIV infection.

Interventions

  • DRUG Leucovorin calcium
  • DRUG Pentamidine isethionate
  • DRUG Sulfamethoxazole-Trimethoprim
  • DRUG Trimetrexate glucuronate

Trial Details

FieldValue
Enrollment Target 364 participants
Est. Completion 1991-09
Phase Phase 3

What the Registry Record Tells You About NCT00001013

The ClinicalTrials.gov registry entry for NCT00001013 describes a study currently listed as completed, categorized as Phase 3. The registered enrollment target is 364 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is National Institute of Allergy and Infectious Diseases (NIAID), which has 2,006 total studies on file at ClinicalTrials.gov.

The record links to 0 conditions, and to 4 interventions - of which Leucovorin calcium is the first listed.

NCT00001013 reports 0 study locations.

Frequently Asked Questions

What is clinical trial NCT00001013 about?

NCT00001013 is a clinical study titled "Comparison of Trimetrexate Plus Leucovorin Calcium Rescue Versus Sulfamethoxazole-Trimethoprim in the Treatment of Pneumocystis Carinii Pneumonia (PCP) in Patients With AIDS". To compare the safety and effectiveness of an investigational drug therapy (trimetrexate plus leucovorin calcium) with that of conventional therapy (sulfamethoxazole-trimethoprim) in the treatment of moderately severe Pneumocystis carinii pneumonia (PCP) in patients who have AIDS, are HIV positive, ...

What is the current status of trial NCT00001013?

This trial is currently completed. It is a Phase 3 study. The enrollment target is 364 participants. Estimated completion is 1991-09.

What interventions are being tested in trial NCT00001013?

The interventions under investigation include: Leucovorin calcium (DRUG), Pentamidine isethionate (DRUG), Sulfamethoxazole-Trimethoprim (DRUG), Trimetrexate glucuronate (DRUG).

Who is sponsoring clinical trial NCT00001013?

This trial is sponsored by National Institute of Allergy and Infectious Diseases (NIAID), which has 2,006 total clinical trials registered on ClinicalTrials.gov.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.