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NCT00000947 · ClinicalTrials.gov registry record · NA

A Study to Evaluate the Effects of Azithromycin on MAC Disease Prevention in HIV-Positive Patients

A NA study, sponsored by National Institute of Allergy and Infectious Diseases (NIAID).

Completed
Registry status
NA
Development phase
850
Enrollment target

NCT00000947: Completed NA study, sponsored by National Institute of Allergy and Infectious Diseases (NIAID).

NCT00000947 is a NA study that has completed, run by National Institute of Allergy and Infectious Diseases (NIAID). The registered enrollment target is 850 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (39% lower). According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT00000947, a NA study, has completed, sponsored by National Institute of Allergy and Infectious Diseases (NIAID).

COMPLETED
Registry status
NA
Development phase
850 participants
Enrollment target

Study Summary

This study is designed to find out whether HIV-positive patients whose immune systems have improved after receiving anti-HIV treatment should take azithromycin to prevent Mycobacterium avium complex (MAC) disease. This study also examines the possibility of putting off MAC prevention treatment in patients who respond well to anti-HIV drug therapy. Azithromycin is approved for the prevention of MAC disease in people with HIV and low CD4 cell counts. However, some people who have taken azithromycin have been found to carry antibiotic-resistant bacteria (germs that can grow despite the presence of drugs used to kill them). It is not known whether the risks associated with taking azithromycin outweigh the risk of getting MAC disease.

Interventions

  • DRUG Azithromycin

Trial Details

FieldValue
Enrollment Target 850 participants
Est. Completion 2000-07
Phase NA

What the finished NCT00000947 record still lists

NCT00000947 is an interventional study that assigns participants to a tested intervention. The registered 850 participants enrollment target is mid-sized for trials with a published cap, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (39% lower).

The record links to 0 conditions, and to 1 intervention - of which Azithromycin is the first listed.

NCT00000947 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT00000947 about?

NCT00000947 is a clinical study titled "A Study to Evaluate the Effects of Azithromycin on MAC Disease Prevention in HIV-Positive Patients". This study is designed to find out whether HIV-positive patients whose immune systems have improved after receiving anti-HIV treatment should take azithromycin to prevent Mycobacterium avium complex (MAC) disease. This study also examines the possibility of putting off MAC prevention treatment in pa...

What is the current status of trial NCT00000947?

This trial is currently completed. It is a NA study. The enrollment target is 850 participants. Estimated completion is 2000-07.

What interventions are being tested in trial NCT00000947?

The interventions under investigation include: Azithromycin (DRUG).

Who is sponsoring clinical trial NCT00000947?

This trial is sponsored by National Institute of Allergy and Infectious Diseases (NIAID), which has 2,006 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT00000947's enrollment target sits among peer trials

850 131st of 2000 higher than 1,869 of 2,000 other NA trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT00000947, the US trial registry maintained by the National Library of Medicine. NCT00000947 (mid enrollment · none site footprint · completed) retrieved and formatted by PlainTrial, see methodology.