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NCT00000823 · ClinicalTrials.gov registry record · Phase 2

A Multicenter Phase II Double-Blind Exploratory Study to Evaluate Differences Among Various Zidovudine/Didanosine Regimens on Quantitative Measures of Viral Burden in Relatively Early HIV-1 Infection

A Phase 2 study, sponsored by National Institute of Allergy and Infectious Diseases (NIAID).

Completed
Registry status
Phase 2
Development phase
85
Enrollment target

NCT00000823: Completed Phase 2 study, sponsored by National Institute of Allergy and Infectious Diseases (NIAID).

NCT00000823 is a Phase 2 study that has completed, run by National Institute of Allergy and Infectious Diseases (NIAID). The registered enrollment target is 85 participants, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (36% lower). According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT00000823, a Phase 2 study, has completed, sponsored by National Institute of Allergy and Infectious Diseases (NIAID).

COMPLETED
Registry status
Phase 2
Development phase
85 participants
Enrollment target

Study Summary

To determine the relative antiviral activity and safety of zidovudine ( AZT ) and didanosine ( ddI ) alone and in combination, as well as in various sequences of administration. The relative efficacy of the approved antiretrovirals in early HIV-1 disease is unclear; thus, a study is needed to evaluate the ability of these various nucleoside analogs to limit pathogenicity.

Interventions

  • DRUG Zidovudine
  • DRUG Didanosine

Trial Details

FieldValue
Enrollment Target 85 participants
Est. Completion 2000-02
Phase Phase 2

What the finished NCT00000823 record still lists

NCT00000823 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 85 participants, a relatively small participant target, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (36% lower).

The record links to 0 conditions, and to 2 interventions - of which Zidovudine is the first listed.

NCT00000823 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT00000823 about?

NCT00000823 is a clinical study titled "A Multicenter Phase II Double-Blind Exploratory Study to Evaluate Differences Among Various Zidovudine/Didanosine Regimens on Quantitative Measures of Viral Burden in Relatively Early HIV-1 Infection". To determine the relative antiviral activity and safety of zidovudine ( AZT ) and didanosine ( ddI ) alone and in combination, as well as in various sequences of administration. The relative efficacy of the approved antiretrovirals in early HIV-1 disease is unclear; thus, a study is needed to evalu...

What is the current status of trial NCT00000823?

This trial is currently completed. It is a Phase 2 study. The enrollment target is 85 participants. Estimated completion is 2000-02.

What interventions are being tested in trial NCT00000823?

The interventions under investigation include: Zidovudine (DRUG), Didanosine (DRUG).

Who is sponsoring clinical trial NCT00000823?

This trial is sponsored by National Institute of Allergy and Infectious Diseases (NIAID), which has 2,006 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT00000823's enrollment target sits among peer trials

85 820th of 2000 higher than 1,179 of 2,000 other Phase 2 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Phase 2 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT00000823, the US trial registry maintained by the National Library of Medicine. NCT00000823 (small enrollment · none site footprint · completed) retrieved and formatted by PlainTrial, see methodology.