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NCT00000814 · ClinicalTrials.gov registry record · Phase 1
A Comparative Study of Combination Antiretroviral Therapy in Children and Adolescents With Advanced HIV Disease
A Phase 1 study, sponsored by National Institute of Allergy and Infectious Diseases (NIAID).
- Completed
- Registry status
- Phase 1
- Development phase
- 390
- Enrollment target
NCT00000814 is a Phase 1 study that has completed, run by National Institute of Allergy and Infectious Diseases (NIAID). The registered enrollment target is 390 participants.
The verdict
NCT00000814, a Phase 1 study, has completed, sponsored by National Institute of Allergy and Infectious Diseases (NIAID).
- COMPLETED
- Registry status
- Phase 1
- Development phase
- 390 participants
- Enrollment target
Study Summary
To compare the antiviral activity, safety, toxicity, and steady-state pharmacokinetics of zidovudine, didanosine, and nevirapine used in combination in patients with HIV infection. The duration of clinical benefit from zidovudine (AZT) may be limited because of development of viral resistance to the drug. Use of combination antiretroviral therapy can potentially reduce viral load and prevent emergence of multidrug resistance.
Interventions
- DRUG Zidovudine
- DRUG Didanosine
- DRUG Nevirapine
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 390 participants |
| Est. Completion | 1998-11 |
| Phase | Phase 1 |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT00000814
The ClinicalTrials.gov registry entry for NCT00000814 describes a study currently listed as completed, categorized as Phase 1. The registered enrollment target is 390 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is National Institute of Allergy and Infectious Diseases (NIAID), which has 2,006 total studies on file at ClinicalTrials.gov.
The record links to 0 conditions, and to 3 interventions - of which Zidovudine is the first listed.
NCT00000814 reports 0 study locations.
Frequently Asked Questions
What is clinical trial NCT00000814 about?
NCT00000814 is a clinical study titled "A Comparative Study of Combination Antiretroviral Therapy in Children and Adolescents With Advanced HIV Disease". To compare the antiviral activity, safety, toxicity, and steady-state pharmacokinetics of zidovudine, didanosine, and nevirapine used in combination in patients with HIV infection. The duration of clinical benefit from zidovudine (AZT) may be limited because of development of viral resistance to th...
What is the current status of trial NCT00000814?
This trial is currently completed. It is a Phase 1 study. The enrollment target is 390 participants. Estimated completion is 1998-11.
What interventions are being tested in trial NCT00000814?
The interventions under investigation include: Zidovudine (DRUG), Didanosine (DRUG), Nevirapine (DRUG).
Who is sponsoring clinical trial NCT00000814?
This trial is sponsored by National Institute of Allergy and Infectious Diseases (NIAID), which has 2,006 total clinical trials registered on ClinicalTrials.gov.
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