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NCT00000731 · ClinicalTrials.gov registry record · NA

Evaluation of the Interaction Between Acetaminophen and Zidovudine

A NA study of HIV Infections, sponsored by National Institute of Allergy and Infectious Diseases (NIAID).

Completed
Registry status
NA
Development phase
10
Enrollment target
1
Study location

NCT00000731: Completed NA study of HIV Infections, sponsored by National Institute of Allergy and Infectious Diseases (NIAID).

NCT00000731 is a NA study of HIV Infections that has completed, run by National Institute of Allergy and Infectious Diseases (NIAID). The registered enrollment target is 10 participants, below the 446-participant average among 542 other HIV Infections trials with a reported enrollment target (98% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT00000731, a NA study of HIV Infections, has completed, sponsored by National Institute of Allergy and Infectious Diseases (NIAID).

COMPLETED
Registry status
NA
Development phase
10 participants
Enrollment target
1
Study location

Study Summary

To determine if zidovudine (AZT) and acetaminophen (APAP) interact when given to the same patient, and if so, the manner of interaction. Patients with AIDS often require therapy with painkillers for the management of mild pain and discomfort associated with their disease, and APAP is often prescribed. AZT is being used to treat AIDS patients. It is important for doctors to understand how AZT and APAP may interact when given to the same patient, because other studies have suggested that the dosage of AZT may have to be adjusted when given with APAP in order to avoid or minimize adverse effects.

Conditions Studied

Interventions

  • DRUG Acetaminophen
  • DRUG Zidovudine

Study Locations (1)

Pennsylvania

  • Univ of Pittsburgh Med School - Pittsburgh

Trial Details

FieldValue
Enrollment Target 10 participants
Est. Completion 1990-05
Phase NA

What the finished NCT00000731 record still lists

NCT00000731 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 10 participants, a relatively small participant target, below the 446-participant average among 542 other HIV Infections trials with a reported enrollment target (98% lower).

The record links to 1 condition, with HIV Infections appearing as the primary indexed condition, and to 2 interventions - of which Acetaminophen is the first listed.

NCT00000731 reports a single indexed study location in Pennsylvania.

Frequently Asked Questions

What is clinical trial NCT00000731 about?

NCT00000731 is a clinical study titled "Evaluation of the Interaction Between Acetaminophen and Zidovudine". To determine if zidovudine (AZT) and acetaminophen (APAP) interact when given to the same patient, and if so, the manner of interaction. Patients with AIDS often require therapy with painkillers for the management of mild pain and discomfort associated with their disease, and APAP is often prescribe...

What is the current status of trial NCT00000731?

This trial is currently completed. It is a NA study. The enrollment target is 10 participants. Estimated completion is 1990-05.

What conditions does trial NCT00000731 study?

This clinical trial studies the following conditions: HIV Infections.

What interventions are being tested in trial NCT00000731?

The interventions under investigation include: Acetaminophen (DRUG), Zidovudine (DRUG).

Who is sponsoring clinical trial NCT00000731?

This trial is sponsored by National Institute of Allergy and Infectious Diseases (NIAID), which has 2,006 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT00000731 being conducted?

This trial has 1 study location across Pennsylvania. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Similar trials for HIV Infections

Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.

Where NCT00000731's enrollment target sits among peer trials

10 526th of 542 higher than 14 of 542 other HIV Infections trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other HIV Infections trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT00000731, the US trial registry maintained by the National Library of Medicine. NCT00000731 (small enrollment · single site footprint · completed) retrieved and formatted by PlainTrial, see methodology.